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180-210 / 430 resultsresearch Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ
Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
![Inherited Disorders of the Hair](/images/research/ba0a3944-3bde-466a-8cc0-fa72dccf5855/small/25953.jpg)
research Inherited Disorders of the Hair
The document explains the genetic causes and characteristics of inherited hair disorders.
![Global Landscapes of Human Phenotypic Variation in Inherited Traits](/images/research/2f57bb9b-1bbb-47dd-bbe8-300039f4ee42/small/18330.jpg)
research Global Landscapes of Human Phenotypic Variation in Inherited Traits
Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.
![<i>WNT10A</i> , dermatology and dentistry](/images/research/454da995-4f64-4db8-a24e-3d1020f55b93/small/17134.jpg)
research WNT10A , dermatology and dentistry
Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
![Index](/images/research/3c759193-39cc-4270-98e5-fd7b74fbde8d/small/17585.jpg)
research Index
The document is a detailed medical reference on skin and genetic disorders.
![Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis](/images/research/9ff02f8e-c90a-4308-a80e-abaa2af9e28e/small/29301.jpg)
research Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis
A20 protein is crucial for normal skin and hair development.
![Involvement of Wnt, Eda and Shh at defined stages of sweat gland development](/images/research/1379b7b7-259d-47c2-a181-3e15b6542fbc/small/34120.jpg)
research Involvement of Wnt, Eda and Shh at defined stages of sweat gland development
Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
![Hair Disorders](/images/research/6313e230-3af5-4e7f-9b04-5cbd189c3320/small/17586.jpg)
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
![Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development](/images/research/8229b046-c78a-4d63-b012-19ba4fc73695/small/29265.jpg)
research Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development
Chemokine signaling is important for hair development.
research Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen)
Edar signaling is crucial for controlling hair growth and regression.
![Current Genetics in Hair Diseases](/images/research/f18c85d8-0c3c-47af-b284-91c72bcbe2fb/small/26613.jpg)
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
![Genetics of Alopecia](/images/research/f3a8177a-839e-4ae9-aa6a-d30133aa971c/small/26034.jpg)
research Genetics of Alopecia
Different genes are linked to various types of hair loss.
![Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation](/images/research/fb452ca3-56c6-4b02-b9ad-1fdf57dd3857/small/19846.jpg)
research Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation
Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
research Anatomy and Physiology of Hair
Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
research The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
![Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles](/images/research/04be91fb-e945-4386-b59f-a8509acd5cfc/small/13020.jpg)
research Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
![New-Generation Therapies for the Treatment of Hair Loss in Men](/images/research/7209574c-746b-4381-a2fc-e52adba95077/small/13631.jpg)
research New-Generation Therapies for the Treatment of Hair Loss in Men
New treatments for male hair loss show promise but need more research for safety and effectiveness.
![Molecular Genetic and Endocrine Mechanisms of Hair Growth](/images/research/6fba3462-6b18-416c-adba-3d5a16d005a7/small/25106.jpg)
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
![To grow or not to grow: Hair morphogenesis and human genetic hair disorders](/images/research/1e602d4a-a7ab-4ef5-92d5-a3a9308e754d/small/19745.jpg)
research To grow or not to grow: Hair morphogenesis and human genetic hair disorders
Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
![Developmental genetics of color pattern establishment in cats](/images/research/b58e6d5e-04f8-478f-b02c-e3b9661c44ee/small/30646.jpg)
research Developmental genetics of color pattern establishment in cats
Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
![Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells](/images/research/67ff6ccd-1b3f-460a-90d6-d7b505399500/small/12673.jpg)
research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells
Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
![Wnt target gene Ascl4 is dispensable for skin appendage development](/images/research/51366c1c-f2fa-4660-8b4c-ab3c9e10ee87/small/35067.jpg)
research Wnt target gene Ascl4 is dispensable for skin appendage development
The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
![Improving human forensics through advances in genetics, genomics and molecular biology](/images/research/d05bcbc6-c398-46b7-a4d5-86bbb028186b/small/26195.jpg)
research Improving human forensics through advances in genetics, genomics and molecular biology
DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.
![Genetic basis of skin appendage development](/images/research/ef7af60b-9dab-420c-b54a-960777778b64/small/35666.jpg)
research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
![Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)](/images/research/c72e0003-03d6-4afc-82a7-7b779ea469fc/small/30782.jpg)
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
![Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells](/images/research/daf0bb88-390f-447e-9511-873291beadc1/small/12885.jpg)
research Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells
Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
![Long noncoding RNA and gene expression analysis of melatonin-exposed Liaoning cashmere goat fibroblasts indicating cashmere growth](/images/research/615ad42f-b3e9-450d-949d-a435f1b8242e/small/34875.jpg)
research Long noncoding RNA and gene expression analysis of melatonin-exposed Liaoning cashmere goat fibroblasts indicating cashmere growth
Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.
![Identification of key pathways and genes that regulate cashmere development in cashmere goats mediated by exogenous melatonin](/images/research/7e19313c-d1b4-4a36-8f69-bb201d0ed89d/small/34846.jpg)
research Identification of key pathways and genes that regulate cashmere development in cashmere goats mediated by exogenous melatonin
Melatonin affects cashmere growth in goats by influencing stem cell and certain signaling pathways.
![Clinical and molecular genetic studies in hereditary hair loss](/images/research/bb1d9e6d-77a0-43a0-a60f-362c7f322999/small/28958.jpg)
research Clinical and molecular genetic studies in hereditary hair loss
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.