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    Glossary EDA gene

    gene crucial for developing skin, hair, teeth, and sweat glands

    The EDA gene, or ectodysplasin A gene, is responsible for producing a protein that plays a crucial role in the development of skin, hair, teeth, and sweat glands. Mutations in this gene can lead to conditions like X-linked hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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    Research 30 of 569

    1. Novel missense mutation in the EDA gene in a family affected by oligodontia 2016 · 12 citations
    2. Next-generation Sequencing Identified a Novel EDA Mutation in a Chinese Pedigree of Hypohidrotic Ectodermal Dysplasia with Hyperplasia of the Sebaceous Glands Acta dermato-venereologica · 2017 · 4 citations
    3. Mutational spectrum of EDA, EDAR, EDARADD, and WNT10A genes in the largest cohort of Russian patients with hypohidrotic ectodermal dysplasia Orphanet Journal of Rare Diseases · 2026
    4. Estudo da diversidade dos genes MC1R e SLC24A5 em populações globais: avaliação de aspectos evolutivos e ambientais 2017
    5. EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes 2020 · 12 citations
    6. Farmácia da Cruz, Porto e Serviços Farmacêuticos do Hospital General Universitario Gregorio Marañón, Espanha Open Repository of the University of Porto (University of Porto) · 2024
    7. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    8. Advances in the genetic understanding of hypohidrotic ectodermal dysplasia Expert opinion on orphan drugs · 2017 · 1 citations
    9. Current Genetics in Hair Diseases InTech eBooks · 2013 · 1 citations
    10. EDA Missense Variant in a Cat with X-Linked Hypohidrotic Ectodermal Dysplasia Genes · 2024
    11. Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis Development · 2000 · 208 citations
    12. Genetics of Alopecia Encyclopedia of Life Sciences · 2012
    13. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development 2012 · 48 citations
    14. ALOPECIA ANDROGENÉTICA: DIAGNÓSTICO, TERAPIAS CLÍNICAS E PROCEDIMENTOS ESTÉTICOS Editora Pasteur eBooks · 2026
    15. Ancient lineages of the keratin-associated protein (KRTAP) genes and their co- option in the evolution of the hair follicle Research Square (Research Square) · 2022
    16. A ALOPECIA AREATA E SUA RELAÇÃO COM A GEOGRAFIA E A PROMOÇÃO DA SAÚDE Hygeia - Revista Brasileira de Geografia Médica e da Saúde · 2017 · 1 citations
    17. Avaliação do perfil fenotípico, proliferativo e secretório de células-tronco mesenquimais do tecido adiposo captadas por lipoaspiração assistida por laser 2023
    18. Mutational spectrum in 101 patients with hypohidrotic ectodermal dysplasia and breakpoint mapping in independent cases of rare genomic rearrangements Journal of Human Genetics · 2016 · 30 citations
    19. Ectodysplasin research—Where to next? Seminars in Immunology · 2014 · 30 citations
    20. Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses Archives of Dermatology · 2001 · 23 citations
    21. A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia: Figure 1 Journal of Medical Genetics · 2012 · 17 citations
    22. Molecular cloning,sequence analysis and expression of goat Edagene Journal of Northwest A & F University · 2012
    23. Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies International reviews of immunology · 2015 · 9 citations
    24. Development and Maintenance of Epidermal Stem Cells in Skin Adnexa International journal of molecular sciences · 2020 · 15 citations
    25. Interplay between EDA-EDAR and WNT signalling pathways in the development of skin appendages in hypohidrotic ectodermal dysplasia Pediatria i Medycyna Rodzinna · 2025 · 1 citations
    26. A novel EDA variant that causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family BMC Pregnancy and Childbirth · 2025
    27. PSICODERMATOSES E A PREVALÊNCIA DE ANSIEDADE: REVISÃO DE LITERATURA Revista Ibero-Americana de Humanidades, Ciências e Educação · 2023
    28. Inherited Disorders of the Hair Elsevier eBooks · 2013 · 2 citations
    29. A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia Journal of Biological Research · 2019 · 11 citations
    30. Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes Developmental biology · 2008 · 117 citations