13 citations
,
July 2009 in “Pediatrics in Review” This review discusses the diagnosis and treatment of 21-hydroxylase deficiency in congenital adrenal hyperplasia and emphasizes the need for earlier detection and proper management; it reports no clinical results.
10 citations
,
March 2019 in “Human Genetics” This study identified a genetic variant in the SGK3 gene related to hairlessness in Scottish Deerhounds, suggesting a similar role for androgen-independent hair loss in humans.
5 citations
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May 2014 in “Clinical and Experimental Dermatology” This study found that novel compound heterozygous mutations in the desmoplakin gene lead to hair shaft abnormalities and can result in lethal cardiomyopathy.
2 citations
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July 2022 in “Indian Journal of Dermatology Venereology and Leprology” This study found that patients with premature greying of hair had significant abnormalities in cardiovascular risk markers, including elevated IL-6 levels, compared to healthy controls.
July 2026 in “European Urology Focus” This study found a significant association between baldness patterns, particularly vertex and early-onset baldness, and an increased risk of prostate cancer.
February 2026 in “South Asian Research Journal of Biology and Applied Biosciences” In this study, patients with alopecia areata had significantly higher levels of luteinizing hormone and follicle-stimulating hormone compared to healthy controls, suggesting a link between hormone levels and the disease.
April 2023 in “Elsevier eBooks” This review discusses the potential male equivalent of polycystic ovary syndrome, examining early-onset androgenic alopecia as a marker and current research on risks and diagnostic recommendations, but it reports no new results.
August 2017 in “Revista de la Facultad de Ciencias Médicas (Quito)/Revista de la Facultad de Ciencias Médicas” This study found that men with early-onset androgenetic alopecia before age 31 have a significantly increased risk of developing prostate cancer.
May 2011 in “Expert Review of Endocrinology & Metabolism” Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.
December 2024 in “JEADV Clinical Practice” This study found that male patients with androgenetic alopecia were associated with an increased risk of varicose veins, but not other major vascular diseases.
This study found that early-onset androgenetic alopecia is associated with higher prevalence of metabolic syndrome, atheroma plaques, and urinary symptoms related to prostate growth compared to controls.
13 citations
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July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified four drugs, including brequinar and abiraterone acetate, that inhibited SARS-CoV-2 infection in vitro, providing potential candidates for repurposing to treat COVID-19.
July 2024 in “Skin Appendage Disorders” This study reviews literature showing that trichotillomania significantly reduces quality of life and emphasizes that effective treatment requires an interdisciplinary approach involving dermatology and psychiatry to address its psychiatric component.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified five FDA-approved drugs, including cepharantine and clofazimine, as potential COVID-19 therapies through in silico and in vitro screening targeting viral entry mechanisms.
13 citations
,
January 2019 in “Indian Journal of Dermatology” This study found that men with early-onset androgenic alopecia had a higher prevalence of cardiovascular risk factors, indicating that early screening for metabolic syndrome may be beneficial in this population.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This study highlights how combining genetic and environmental risk assessments could advance early screening and personalized prevention for vitiligo, given its genetic complexity and environmental interactions.
June 2025 in “Cermin Dunia Kedokteran” This study emphasizes the importance of early detection and cross-sector collaboration in preventing suicide among adolescents, highlighting the role of health professionals, screening tools, and family support systems.
153 citations
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June 2015 in “GenomeBiology.com” This study found that both genome-wide screening methods identified the VTRNA2-1 epiallele as highly responsive to environmental influences, suggesting a link between early embryonic environment, epigenetic changes, and human disease.
15 citations
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May 2010 in “Actas Dermo-Sifiliográficas” This study found that men with early-onset androgenetic alopecia had a higher prevalence of metabolic syndrome and carotid atheromatous plaques than control subjects, suggesting a need for cardiovascular screening in this group.
1 citations
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August 2009 in “ACTUALIDAD MEDICA” In this study, early-onset androgenetic alopecia patients showed a higher prevalence of metabolic syndrome and carotid atheromatosis compared to a control group, suggesting the need for cardiovascular risk screening in this population.
July 2024 in “jurnal ABDIMAS Indonesia” In this study, the authors observed that among elderly participants, 59.1% did not experience depression, correlating with measured average levels of apolipoprotein A and B. They suggest early screening can help manage apolipoprotein levels, potentially reducing depression risk and improving quality of life.
23 citations
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March 2010 in “Actas Dermo-Sifiliográficas” In this study, early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid atherosclerosis compared to controls, suggesting cardiovascular screening might be beneficial for this group.
February 2009 in “Journal of The American Academy of Dermatology” AGA patients have higher rates of metabolic syndrome and carotid atheromatosis, suggesting early screening and prevention is important.
March 2026 in “Journal of Pakistan Association of Dermatologists” This study found that androgenic alopecia is highly prevalent in women with PCOS, suggesting early dermatological screening could help identify related metabolic and psychosocial risks.
28 citations
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November 2014 in “Current Diabetes Reports” This review discusses the complex links between polycystic ovary syndrome, insulin resistance, and potential metabolic risks starting in adolescence, noting the need for early screening and treatment but reports no new clinical results.
April 2026 in “Frontiers in Medicine” In this study, young female medical students at King Saud University reported a higher prevalence of physician-diagnosed PCOS compared to similar Western populations, and hirsutism was notably associated with the condition, highlighting the need for early screening and health education.
December 2025 in “Journal of Skin and Stem Cell” This study found a higher prevalence of lipid abnormalities in individuals with androgenetic alopecia, especially in severe cases, highlighting the need for early screening and treatment to prevent cardiovascular complications.
September 2025 in “Cureus” This study found that 19.5% of young girls screened using the Rotterdam criteria were diagnosed with polycystic ovarian syndrome, highlighting the importance of early screening and intervention.
January 2024 in “African Journal of Biomedical Research” In this study of pregnant women in Pampore, Kashmir, 90% were found to have hypothyroidism, with 75% of thyroid dysfunction cases being diagnosed during pregnancy. The study highlights the need for better nutrition and early screening to manage gestational thyroid dysfunction effectively.
January 2023 in “Annals of Dermatology” This study found that males with a maternal history of androgenetic alopecia were significantly more likely to have female pattern hair loss, suggesting early screening might be beneficial.