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ERG increases SOX9, promoting prostate cancer growth and invasion.

Baricitinib reduces inflammation and improves cell health in premature aging cells.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

Ectodysplasin signaling is crucial for skin appendage development, requiring specific doses and durations.

Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.

Chromosomal microarray analysis is important for diagnosing rare genetic variations and guiding treatment.

A person got uncombable hair syndrome from two copies of chromosome 1 from their mother.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

The document covers all aspects of plastic and reconstructive surgery, from basic techniques to specific procedures for various body parts.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

The document reports a unique case of woolly hair with a combination of conditions not previously seen together.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

New treatments for hair loss are promising.

Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.

Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.

Reflectance confocal microscopy is useful for diagnosing and monitoring skin diseases, but it has limitations and requires expertise for correct use.