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The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Mice with human skin protein K8 had more skin problems and cancer.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.

PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.

Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Using neurohormones to control keratin can lead to new skin disease treatments.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.