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In this case series, dual-targeted therapy was observed to provide promising clinical responses in refractory inflammatory bowel disease, with 88.23% to 100% response rates across 9 months and an endoscopic response in 88.89% of evaluated patients, though some adverse events occurred.

This study found that the DNN-DTIs prediction model achieved high accuracy in predicting drug-target interactions, suggesting its potential application in drug repositioning and the discovery of new uses for existing drugs.

In 2013, the FTC settled with hair company Bosley over claims it illegally shared business information with a competitor.

In this case study, researchers detailed two Saudi cases of the ultra-rare Trichohepatoneurodevelopmental syndrome, identifying pathogenic variants in the CCDC47 gene and reinforcing a strong gene-disease association, which helps clarify the disorder's clinical features and genetic mutations.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This review systematically analyzed literature to differentiate desmoplastic trichoepitheliomas from other cutaneous tumors based on clinical, histopathological, and immunohistochemical features but reports no new clinical results.

In this report, a 54-year-old woman with familial dyskeratotic comedones showed slight improvement in skin lesions after topical retinoids and urea cream. This source also describes the first dermoscopic findings for this condition and reviews 21 previous cases.

This report suggests that TCDD may alter human epidermal stem cell populations by upregulating c-Myc, potentially leading to increased stem cell turnover during chloracne development.

The study found that different criteria led to different patient groups in the CombAT study compared to the MTOPS study.

In this study, researchers analyzed social media data to assess the comparative safety of arthritis medications, finding increased odds of herpes zoster and perforated bowel with certain therapies. Social media posts expressed more safety concerns than favorable opinions about drug safety.

VYC-12L effectively improves skin smoothness, reduces fine lines, and boosts hydration.

This study found that low-dose radioactive iodine therapy for hyperthyroidism and thyroid cancer produced short-term adverse effects like loss of taste, xerostomia, and hair loss, which were self-limiting.

Temporal triangular alopecia is a non-scarring hair loss seen in some Asian children.

In this case study, a 51-year-old Japanese man was diagnosed with desmoplastic trichoepithelioma after histological examination of surgically excised facial plaques.

In this study, the varied phenotype of trichothiodystrophy was highlighted, with findings of distinctive hair shaft abnormalities and a wide range of multisystem issues, including neurologic and urologic disorders.

This study found that betibeglogene autotemcel significantly improved transfusion independence in 89% of patients with transfusion-dependent beta-thalassemia, although the high cost and manufacturing challenges may limit widespread adoption.

This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.

This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.

This study found that administering tolerogenic dendritic cell-conditioned medium to dihydrotestosterone-treated mice promoted hair regrowth by modulating the follicular microenvironment, reducing pro-inflammatory cytokines, and activating key signaling pathways, highlighting its potential as a treatment for androgenetic alopecia.

This study observed that DNA damage response (DDR) plays a key role in pressure overload-induced cardiomyocyte hypertrophy, with disruption of the ATM kinase pathway potentially modulating this hypertrophy in mice.

A new method improves the isolation of hair follicle cells for better hair growth research.

This correspondence comments on the unknown prevalence of permanent alopecia following high-dose docetaxel chemotherapy and highlights the need for further understanding and prevention strategies.

This study in mice suggests that defects in hair follicles with mesenchymal TSC2 disruption may result from an impaired TGFβ1 response, indicating a potential novel treatment approach for tuberous sclerosis complex.

The study demonstrated that both DKK2 and SOSTDC1 are necessary for normal timing of the first catagen phase in mice hair growth cycles.

This study developed a DPC cell line by introducing mutant CDK4, Cyclin D1, and TERT, making it a promising tool to study downstream signaling pathways activated by testosterone in androgenetic alopecia.

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

This study found that the cytoplasmic dynein component Dynlt3 is essential for effective melanosome transport and transfer in mouse melanocytes, linking melanosome positioning and acidity to the Wnt/β-catenin signaling pathway.

This case report documents a rare instance of triangular temporal alopecia in an adult woman, emphasizing the importance of correct diagnosis to avoid unnecessary treatments, and reviews the literature on TTA.

This case report describes a 2-year-old boy diagnosed with trichothiodystrophy, characterized by fragile hair, intellectual damage, diminished fertility, and short stature.

This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.