research Novel Therapies for Alopecia Areata: The Era of Rational Drug Development
New targeted therapies for hair loss from alopecia areata show promise, with personalized treatment expected in the future.
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research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Leflunomide: An Unlikely Trigger and Mechanistically a Beneficial Drug for Alopecia Areata
Leflunomide is more likely to help treat alopecia areata than cause it.
research Intradermal Injections of a Hair Growth Factor Formulation for Enhancement of Human Hair Regrowth: Safety and Efficacy Evaluation in a First-in-Man Pilot Clinical Study
The QR 678 hair growth treatment was safe and effective for hair regrowth in men and women.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Patients Treated for Male Pattern Hair Loss with Finasteride Show Altered Levels of Neuroactive Steroids in Cerebrospinal Fluid and Plasma After Discontinuation
Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
research Systematic Review of Platelet-Rich Plasma in Treating Alopecia: Focusing on Efficacy, Safety, and Therapeutic Durability
Platelet-rich plasma (PRP) is a safe and potentially effective way to treat hair loss, especially when combined with minoxidil.
research A Randomized, Blinded, Three-Arm, Multicenter Trial Comparing the Efficacy and Safety of Fluconazole Given Once Daily for 3 or 6 Weeks with Griseofulvin Given Once Daily for 6 Weeks in Pediatric Patients with Tinea Capitis
The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
research 5-Alpha Reductase Inhibitors in Androgenetic Alopecia: Shifting Paradigms, Current Concepts, Comparative Efficacy, and Safety
Dutasteride works better than finasteride for hair loss, with both being safe to use.
research Tolerability of Hair Cleansing Conditioners: A Double-Blind Randomized Controlled Trial Evaluating Consumer Complaints to the U.S. Food and Drug Administration
Wen by Chaz Dean Sweet Almond Mint Cleansing Conditioner is better tolerated than salicylic acid and baby shampoos.
research Teriflunomide in Multiple Sclerosis: An Update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research The Safety and Efficacy of Diphencyprone for the Treatment of Alopecia Areata in Children
Diphencyprone can help some children with alopecia areata regrow hair, but it often causes side effects.
research Efficacy and Safety of SER120 Nasal Spray in Patients with Nocturia: Pooled Analysis of Two Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trials
SER120 nasal spray effectively reduces nighttime urination and is safe for patients.
research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research Final Report on the Safety Assessment of Human and Animal Placental and Umbilical Extracts in Cosmetics
The safety of placental and umbilical extracts in cosmetics is uncertain, requiring more research.
research Polymeric Nanohydrogel in Topical Drug Delivery System
Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.
research Androgenetic Alopecia: An Update Of Treatment Options
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
research Therapeutic Efficacy and Safety of Kang-Ai Injection Combined with Platinum-Based Doublet Chemotherapy in Advanced NSCLC: A Meta-Analysis
Kang-ai injection with platinum-based chemotherapy improves tumor response and immune function while reducing side effects in advanced lung cancer.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Drug Survival and Long-Term Outcome of Tofacitinib in Patients with Alopecia Areata: A Retrospective Study
Tofacitinib is effective and safe for treating alopecia areata with a good drug survival rate.
research Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges
Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.
research Efficacy and Safety of Minoxidil 2% Solution in Combination With a Botanical Hair Solution in Women With Female Pattern Hair Loss/Androgenic Alopecia
Using Minoxidil 2% solution with a botanical hair solution twice daily can significantly improve hair growth and quality in women with Female Pattern Hair Loss, boosting self-confidence and attractiveness.
research Drug-Induced Hair Changes
Some drugs can cause changes to your hair.
research Efficacy and Safety of Botulinum Toxin A in the Treatment of Female Pattern Hair Loss
Botulinum toxin A has limited effectiveness for 3 months in treating female pattern hair loss and may reduce scalp oiliness.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Drug Repurposing Patent Applications April–June 2021
Drug repurposing shows promise for treating many medical conditions.
research Faculty Opinions Recommendation of Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients
research Faculty Opinions Recommendation of Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients
research Drug Polymorphism Identification Using Fourier Transform-Raman Spectroscopy: A Comparative Study of Lamivudine and Finasteride Drugs
FT-Raman spectroscopy is effective for identifying drug polymorphs, ensuring quality and stability.
research Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages
Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.