research An In-Depth Study of DOPE:DOPC Liposomes to Maximize Targeted Drug Delivery to Cancer-Associated Cells
DOPE:DOPC liposomes can improve targeted cancer drug delivery, reducing side effects and increasing effectiveness.
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research Time-Tracking-Based Research of Drug Development in Pharmaceutical Fields: A Case Study on Metformin
The conclusion is that metformin may be useful for treating various conditions beyond diabetes and that time-tracking analysis is a good way to review drug research.
research Nanospanlastic as a Promising Nanovesicle for Drug Delivery
Nanospanlastics are effective in targeted drug delivery for chronic diseases, improving skin conditions, treating hair loss, and increasing drug absorption.
research Drugs Associated the Most with Male-Factor Infertility: Assessment of the 2010-2020 Food and Drug Administration Pharmacovigilance Database
Finasteride and testosterone are the drugs most linked to male infertility, but many other potential drugs may be under-reported.
research A Simple Decision Tree for Identifying Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation
The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.
research Modeling the Pharmacodynamics of Nandrolone Doping Drug and Implications for Anti-Doping Testing
The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.
research Faculty Opinions Recommendation of Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific T cell receptor linked to severe drug reactions like Stevens-Johnson syndrome when patients take carbamazepine.
research A Case of Telogen Effluvium Associated with Drug-Induced Hyperprolactinemia
A woman's temporary hair loss was caused by high prolactin levels from her medication.
research A Prospective Observational Study on Drug Safety Monitoring and Pharmacoeconomics in Patients with Locally Advanced Unresectable NSCLC in a Tertiary Care Hospital
Carboplatin-paclitaxel is preferred for advanced lung cancer due to its balance of affordability and patient well-being.
research Peer Review of Computational Drug Repositioning Based on Side-Effects Mined from Social Media
The peer review highlighted the need for clearer data handling, questioned the study's validity, and recognized improvements from the original version.
research Peer Review of Computational Drug Repositioning Based on Side-Effects Mined from Social Media
Reviewers suggested the study on finding new drug uses through social media side-effects needs better methods and clearer limitations.
research Peer Review of Computational Drug Repositioning Based on Side-Effects Mined from Social Media
The study improved and was accepted despite initial concerns about data clarity, methodology, and potential overfitting.
research Peer Review of Computational Drug Repositioning Based on Side-Effects Mined from Social Media
Reviewers criticized the study's methods and suggested focusing on drug mechanisms instead of repositioning due to social media data quality concerns.
research Peer Review of Computational Drug Repositioning Based on Side-Effects Mined from Social Media
Reviewers criticized the study for its assumptions, social media data collection issues, and lack of comparison to existing methods.
research FDA Declines Approval of Testosterone Drug for Third Time
The FDA did not approve a testosterone drug because of safety concerns.
research Hair Loss Effects and Surgical/Drug Treatments for Alopecias
Hair loss can cause emotional and social issues, and various treatments, including medication, surgery, and psychological support, are needed.
research Cerebral Ischemia Related to Isotretinoin; Venlafaxine-Induced Alopecia; Cognitive Dysfunction with Tolterodine; Retinal Artery Occlusion After Injection of Long-Acting Risperidone; Olanzapine-Induced Chylomicronemia Presenting as Pancreatitis; Metabolic Effects of the Atypical Antipsychotics – An Editorial; Another Drug-Induced Pancreatitis – This One Caused by a Tyrosine Kinase Inhibitor; Suicide Attempts Related to Antidepressant Medications
The conclusion is that healthcare professionals should report adverse drug reactions to improve medication safety and patient care.
research The Chinese State Food and Drug Administration Has Issued Sinovac Biotech a New Drug Certificate Approving Its Split Influenza Vaccine
China approved Sinovac's flu vaccine, Japan approved RiUP for female hair loss, and Nippon Kayaku's three cancer drugs.
research Finasteride-Loaded Nano-Lipidic Carriers for Follicular Drug Delivery: Preformulation Screening and Box-Behnken Experimental Design for Optimization of Variables
Optimized carriers effectively deliver Finasteride for hair loss treatment.
research A Comparison of an Herbal Drug and 2% Minoxidil Solution in the Treatment of Androgenetic Alopecia
research JAK Inhibitors in Dermatology: The Promise of a New Drug Class
JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
research Comparison of Stratum Corneum Penetration and Localization of a Lipophilic Model Drug Applied in an O/W Microemulsion and an Amphiphilic Cream
The microemulsion delivered the dye deeper into the skin than the cream.
research Alkylation of Human Hair Keratin for Tunable Hydrogel Erosion and Drug Delivery in Tissue Engineering Applications
Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
research Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study
Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
research Albendazole Treatment of Echinococcosis in Humans: Effects on Microsomal Metabolism and Drug Tolerance
Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.
research Green Regenerative Hydrogel Wound Dressing Functionalized by Natural Drug-Food Homologous Small Molecule Self-Assembled Nanospheres
The new hydrogel dressing with natural molecules helps heal wounds faster and improves skin repair.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Using a Capture–Recapture Method to Assess the Frequency of Adverse Drug Reactions in a French University Hospital
The study found that combining different databases gives a better estimate of drug side effects in hospitals.
research Synthesis and Characterization of Inclusion Complex of the Vasodilator Drug Minoxidil with β-Cyclodextrin
Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
research Morphological Changes in Human Head Hair Subjected to Various Drug Testing Decontamination Strategies
Different hair cleaning methods caused varying levels of damage to the hair's outer layer.