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Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Liposomes could improve how skin care products work but are costly and not very stable.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

EVAL membranes help create cell structures that can regrow hair follicles.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.