1 citations
,
April 2017 in “Journal of Investigative Dermatology” This study found that oral tofacitinib led to variable hair regrowth in patients with resistant alopecia areata, implying that longer treatment durations may be needed to fully assess its effectiveness.
58 citations
,
April 2012 in “Journal of the American Academy of Dermatology” Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.
5 citations
,
November 2019 in “Dermatology and therapy” This review discusses the use of beard hair as a donor source for hair transplantation in hirsute patients and highlights the lack of extensive studies on its efficacy and safety in East Asian populations.
7 citations
,
July 2014 in “Reproductive Biomedicine Online” This study found that, among fertile egg donors, the AR gene CAG polymorphism was associated with differences in antral follicle count but did not impact ovarian response to gonadotrophins.
July 1998 in “Dermatologic Surgery” Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.
48 citations
,
May 2015 in “PLOS ONE” This study found that a genetic test using 5 to 20 SNPs can predict male pattern baldness with variable accuracy in European men, especially those aged 50 and older.
23 citations
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January 2015 in “Stem cells international” This study found that keratin coatings from human hair may improve the colony-forming efficiency of human mesenchymal stem cells by moderating donor variability, suggesting a potential use in clinical applications.
1 citations
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September 2015 in “Aesthetic Surgery Journal” This article discusses advances in hair transplantation techniques, particularly follicular unit extraction (FUE), emphasizing its advantage of avoiding donor site scarring and allowing for short hairstyles.
February 2026 in “Frontiers in Medicine” In this case report, a three-generation family with Gorlin-Goltz syndrome showed a heterozygous PTCH1 splice-donor variant associated with the disease, and two affected relatives benefited from individualized, side-effect-guided dosing of the drug sonidegib, experiencing regression of basal cell carcinoma lesions.
4 citations
,
August 2018 in “Journal of Cosmetic Dermatology” This study observed that actual harvested grafts in hair transplantation yielded more 1-hair follicular units and fewer 3-hair follicular units than originally estimated, with older age and multiple procedures limiting donor scalp harvesting.
48 citations
,
December 2004 in “Differentiation” This study found that cultured dental papilla cells from various mammals can induce hair follicle regeneration and influence tissue formation, with outcomes dependent on donor age, tooth type, and host environment.
8 citations
,
August 2009 in “Pediatric transplantation” This report presents a case where a patient with Omenn syndrome, complicated by cytomegalovirus infection, was successfully treated using reduced intensity conditioning allogeneic HSCT from a sibling donor.
December 2025 in “International Journal of Pharmacology” This review highlights that iPSC-derived artificial platelets offer a promising alternative to platelet-rich plasma for regenerative medicine, with standardized manufacturing and reproducible pharmacological properties, addressing variability issues associated with donor-derived platelets and showing therapeutic potential in preclinical models of osteoarthritis.
December 2023 in “International Journal of Medical Arts” In this study, researchers observed significant morphological and histological differences in transplanted hair follicles compared to native donor follicles post-FUE hair transplantation for androgenetic alopecia, highlighting substantial variations in sebaceous gland and root sheath degeneration at the recipient site.
116 citations
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April 2020 in “Stem Cell Research & Therapy” This study identified highly variable genes in mesenchymal stem/stromal cells that are linked to classic functions like development and inflammation response, suggesting their potential as markers for further potency studies.
May 2023 in “Asian Journal of Transfusion Science” In this study, conducted at a tertiary care hospital in Chennai, adverse events during blood donation were observed in 0.42% of donors, predominantly affecting first-time male donors, and were mostly vasovagal reactions such as giddiness and sweating.
2 citations
,
August 2024 in “JID Innovations” This study suggests that keratinocytes derived from hair follicles of patients with atopic dermatitis provide a useful model for investigating AD-related inflammation, as they showed greater expression changes of AD markers when stimulated with type 2 cytokines compared to those from healthy donors.
12 citations
,
January 2019 in “International Journal of Trichology” This study found that trichoscopy revealed significant differences in certain variables, such as the brown peripilar sign and white peripilar sign, which may aid in diagnosing early and late stages of androgenetic alopecia.
12 citations
,
November 2020 in “Transplant international” In this study, researchers observed that hand and forearm transplantation at Innsbruck Medical University showed variable long-term outcomes, with the severity of rejection episodes impacting patients' well-being and quality of life but not directly correlating with hand function.
34 citations
,
July 2022 in “Gels” This review explores the potential of alginate as a promising alternative to donor tissue for corneal transplantation due to its adaptability, transparency, and low immunogenicity, and discusses how chemical modifications can enhance its properties for use in corneal tissue engineering.
1 citations
,
April 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review proposes that inconsistent findings in androgenic alopecia research are due to variable biopsy location, hair diameter diversity, and hair follicle miniaturization, and suggests ways to improve study methods.
2 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses unique anatomical features and management strategies for crown alopecia but reports no new clinical findings, focusing instead on surgical techniques for natural-looking results and optimal density.
April 2019 in “Journal of Investigative Dermatology” This study found that DPP4 is significantly involved in matrix deposition and fibrosis in human skin fibroblasts, although the exact functions of DPP4 remain unclear.
19 citations
,
December 2023 in “Journal of Investigative Dermatology” In this study, researchers found that the human hair follicle microbiota vary by anatomical compartment and donor age, with specific microbes like S. epidermidis potentially influencing hair follicle functions, which suggests new avenues for therapeutic targeting.
16 citations
,
March 2008 in “International journal of pharmaceutics” This study found that formulation factors like pH, viscosity, and chemical enhancers can significantly influence intrafollicular hydrocortisone permeation in vitro, with higher pH and enhancers reducing follicular contribution.
10 citations
,
April 2010 in “Dermatologic Surgery” This paper contains no findings, serving instead as contact information for a dermatologist with no financial conflicts of interest disclosed.
18 citations
,
March 2018 in “Archives of Plastic Surgery” This article reviews the use of superficial temporal artery island flaps for facial reconstruction and provides a systematic approach for managing composite facial defects, reporting no major complications in 72 patients.
April 2019 in “Journal of Investigative Dermatology” This study found that CYP11A1-derived vitamin D3 analogs inhibit fibroblast proliferation and decrease collagen production through VDR expression, showing potential antifibrotic and antiproliferative activity in human dermal fibroblasts.
January 2012 in “Anales (Reial Acadèmia de Medicina de la Comunitat Valenciana)” This study found that SRD5A2 expression is absent in one third of benign adult prostates and is associated with hypermethylation, suggesting potential personalization of treatment for prostatic diseases based on methylation status.
85 citations
,
July 2002 in “Pigment Cell Research” This review examines cell senescence pathways in melanocytes, highlighting the involvement of telomere attrition, the p16/RB pathway, and cAMP signaling in the context of melanoma development, but reports no new findings.