Evaluation of Morphological and Histological Changes in Transplanted Hair Follicles

    Mahmoud Salah Khalil, Ahmed El Mofty, Mahmoud Nasef, M.O. Eisa, Mostafa Mohamed Khairy
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    Studysummary In this study, researchers observed significant morphological and histological differences in transplanted hair follicles compared to native donor follicles post-FUE hair transplantation for androgenetic alopecia, highlighting substantial variations in sebaceous gland and root sheath degeneration at the recipient site.
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    The study evaluated morphological and histological changes in transplanted hair follicles after Follicular Unit Extraction (FUE) in 15 patients with androgenetic alopecia over 10-14 months. Significant differences were found between donor and recipient sites, including sebaceous gland degeneration (p=0.002) and arrector pili muscle degeneration (p=0.002). Outer and inner root sheath degeneration also showed substantial variation (p<0.001). The findings highlight the noticeable impact of the FUE procedure on transplanted follicles, suggesting the need for further long-term interest and research.
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