1 citations,
December 2022 in “Pharmaceutics” Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.
1 citations,
March 2018 in “Cureus” Scrotal rejuvenation treats aging-related changes in men's scrotum using methods like medication, hair transplantation, and surgery.
July 2020 in “Comparative medicine” NSG mice had the most mites, and genetic factors affect immune response and susceptibility.
18 citations,
April 2010 in “Actas Dermo-Sifiliográficas” Follicular unit hair transplantation is the standard method for natural-looking hair restoration in androgenic alopecia.
13 citations,
May 2004 in “Dermatologic Surgery” The paper concludes that copying the natural direction and angle of hair in transplants is key for a natural look and doesn't harm hair survival.
June 2004 in “Dermatologic Surgery” Dr. Walter P. Unger suggests that copying a person's natural hair direction and angle during transplants leads to a more natural and fuller appearance.
62 citations,
April 2008 in “Neurobiology of aging” Scientists found a gene in mice that causes early hearing loss.
54 citations,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
September 2019 in “Journal of Investigative Dermatology” Researchers successfully used nude mice to study human hair growth, which could help with future hair research.
32 citations,
September 1997 in “Dermatologic Surgery” Mini-micrografting in hair transplants can give similar density to older methods with fewer sessions.
21 citations,
April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.
2 citations,
January 2020 in “Methods in molecular biology” Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
Understanding genetics is crucial for treating heart and skin diseases.
75 citations,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
31 citations,
September 2008 in “International Journal of Andrology” 5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
24 citations,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
17 citations,
June 2002 in “Dermatologic Surgery” Chinese patients have fewer hair follicles than Caucasians, and transplanting hair at 40% of normal density works for natural-looking hairlines.
14 citations,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
13 citations,
January 2013 in “Applied and Environmental Microbiology” A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.
11 citations,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
6 citations,
June 2012 in “Physiology” The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.
1 citations,
November 2022 in “Pharmaceutical research” The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
Finding functions for unknown GPCRs is hard but key for making new drugs.
August 2020 in “Research Square (Research Square)” Neural progenitor cell-derived nanovesicles help hair growth by activating a key signaling pathway.
June 2002 in “Dermatologic Surgery” Chinese scalps have fewer hair clusters than Caucasians, and transplanting 30 clusters per square centimeter creates a natural-looking hairline for bald Chinese individuals.
835 citations,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
316 citations,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
139 citations,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
130 citations,
September 2018 in “Cell Reports” Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
128 citations,
July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.