The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
74 citations
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April 2002 in “PubMed” This study found that the oral contraceptive containing drospirenone (EE/DRSP) was as effective as EE/CPA in reducing acne lesions, sebum production, and hair growth in women with acne.
September 2024 in “Journal of the American Academy of Dermatology” In this prospective, placebo-controlled study, the researchers observed a significant reduction in hair shedding in women after applying the combined topical treatment DA-OTC-002, containing synephrine and TAAR agonists, compared to placebo, showing a 62.5% average reduction with no reported adverse events.
November 2025 in “Journal of Multidisciplinary Healthcare” This study found that combining fire needle therapy with DHT treatment over eight weeks improved lesion severity, scar symptoms, quality of life, and reduced serum inflammatory cytokine levels in patients with moderate-to-severe acne vulgaris compared to using DHT alone.
1 citations
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January 2022 in “Journal of Cancer Therapy” In this study, Ocoxin used alongside chemotherapy may improve patients' tolerance to treatment and their quality of life without significant safety concerns, although further research is needed.
February 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Low-dose oral minoxidil is a promising, safe treatment for various hair diseases, improving hair thickness and density, but more research is needed on long-term side effects and treatment duration.
4 citations
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September 2024 in “BMC Cancer” In this prospective phase II clinical trial, researchers are investigating whether adding dutasteride to combined androgen blockade can improve the response rate and clinical outcomes for patients with androgen receptor-positive recurrent or metastatic salivary duct carcinoma.
December 2006 in “Annales D Endocrinologie” This article reviews clinical and treatment aspects of hyperandrogenism in women, emphasizing the roles of diagnostic practices, combined oral contraceptives, and cyproterone acetate, but introduces no new findings.
February 2009 in “Endocrinology” This study evaluated the use of oral DHEA for treating atrichia pubis and psychological distress in young females with central adrenal insufficiency but reports no new results.
24 citations
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January 2001 in “Dermatologic clinics” This article reviews the use of hormonal therapies in dermatology, specifically focusing on their pathophysiologic rationale, indications, commonly used drugs, and pretreatment evaluations, and it reports no new research findings.
June 2021 in “Journal of dermatology and dermatitis” This study found that among dermatologists surveyed, 51.9% routinely prescribe the psychotropic agent Doxepin for treating geriatric patients with psycho cutaneous conditions.
September 2020 in “Farmacja Polska” This review discusses various applications of foam systems in drug form technology, highlighting their potential to enhance drug solubility and release modifications, but reports no new clinical results.
29 citations
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March 2017 in “International Journal of Women's Dermatology” This review found that combined oral contraceptives and spironolactone are effective treatments for adult acne in women, but noted that oral contraceptives increase the risk of venous thromboembolism and require individual risk assessment before use.
251 citations
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October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
64 citations
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January 1985 in “Clinical endocrinology” In this study, treatment with the oral contraceptive containing 30 μg ethinyl oestradiol and 150 μg desogestrel significantly reduced androgen-dependent hair growth in hirsute women over one year.
July 2023 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study evaluated the resin oil of Copaifera officinalis L., identifying 64 compounds and developing validated analytical methods for quality control, and formulated a stable pharmaceutical foam, laying groundwork for potential clinical applications of copaiba oil.
82 citations
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January 2000 in “Hormone Research in Paediatrics” This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.
February 1999 in “Drugs in R & D” The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.
164 citations
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January 2003 in “Drugs” 4 citations
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August 2011 in “The Lancet Oncology” Off-label drug use can be risky and requires careful consideration to ensure patient safety.
7 citations
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September 1988 in “Baillière's clinical obstetrics and gynaecology” This article discusses the mechanisms of hirsutism and acne in women, highlighting cyproterone acetate with ethinyloestradiol as an effective anti-androgen therapy in the UK, but it reports no new clinical findings.
1 citations
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August 2016 This study investigated the cytotoxic effects of DHA derivatives on cancer cell lines and found that didocosahexaenoin was the most potent, inducing apoptosis and producing reactive oxygen species in PC3 prostate carcinoma cells.
219 citations
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January 2006 in “Drug Metabolism Reviews” This review discusses how dehydroepiandrosterone (DHEA) may exert its biological effects through multiple receptors and reports no new clinical results.
January 2016 in “The Korean Journal of Internal Medicine” This case report presents the first instance in Korea of unilateral gynecomastia and breast pain associated with doxazosin use.
50 citations
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December 2022 in “Food Chemistry Advances” This review discusses diosgenin's potential benefits for several chronic diseases and emphasizes extraction and quantification techniques, but reports no clinical findings.
1 citations
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February 2023 in “Russian Journal of Bioorganic Chemistry” In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.
13 citations
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August 2016 in “Reproduction” In this study, nandrolone decanoate treatment in rats caused persistent diestrus and altered steroid receptor expression and sex hormones, especially at higher doses, with partial reversibility at lower doses over time.
9 citations
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April 2021 in “Climacteric” This study provides a guideline for the safe and effective use of testosterone in women with hypoactive sexual desire disorder, recommending systemic transdermal testosterone for appropriate candidates while highlighting the importance of informed consent and monitoring due to unestablished long-term safety.
1 citations
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May 2013 in “Oncology Times” This narrative review reflects on the challenges faced by FDA's Oncologic Drugs Advisory Committee members, highlighting public pressure, decision-making complexity, and the evolving landscape of cancer drug development.
2 citations
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March 2004 in “Reviews in Gynaecological Practice” This review discusses treatments for female sexual dysfunction in postmenopausal women, noting that the effectiveness of current pharmaceutical options is inconclusive and emphasizing the importance of individualized care.