1 citations
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June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a cimetidine 10% cream with sodium lauryl sulphate significantly increased drug diffusion through mouse skin and showed promise in treating warts in a preliminary clinical trial.
5 citations
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August 1999 in “Disease-a-month” This review provides guidelines for physicians on using hormonal therapies, such as androgen receptor blockers and oral contraceptives, to treat hormonally related acne, but reports no new clinical findings.
This study observed that, after 90 hours of light exposure, Finasteride retained 57% of its concentration, whereas Diclofenac and Naproxen retained only 12% and 9%, respectively.
January 2006 in “Zhongguo yaofang” This study concluded that the market for 5α-reductase inhibitors, including finasteride, epristeride, and dutasteride, is expected to grow with promising prospects.
December 2025 in “Scientific Reports” In this study, researchers observed that DHEA-induced PCOS rats experienced significant changes in gut microbiota and metabolic profiles, particularly affecting steroid and lipid metabolism, suggesting the gut-ovary axis may play a role in the pathogenesis of PCOS.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that spironolactone, a potassium-sparing diuretic with antiandrogenic activity, effectively improves hair density, reduces shedding, and stabilizes symptoms in female pattern hair loss, though symptoms often recur after discontinuation, suggesting the need for sustained therapy.
July 2025 in “Future Journal of Pharmaceuticals and Health Sciences” This study developed a polyherbal chocolate formulation aimed at managing PCOS and hormonal balance, finding that formulation F2 showed excellent organoleptic properties and stability, with future in vivo studies being suggested.
4 citations
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October 1988 in “Clinics in Dermatology” This paper reviews current knowledge about androgens' role in androgenic alopecia and female hirsutism but presents no new clinical findings.
13 citations
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June 2023 in “Frontiers in Pharmacology” This meta-analysis reports that trastuzumab deruxtecan is effective and has an acceptable safety profile for treating HER2-low or positive advanced breast cancer, although further research is recommended to support individualized treatment strategies.
29 citations
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July 2009 in “BJU international” This review examines the pharmacological properties and potential clinical benefits of 5α‐reductase inhibition in prostate cancer but reports no new research findings.
December 2025 in “Journal of Veterinary Clinics” This case report describes the use of CO2 laser surgery to treat chronic pododermatitis and pseudopads in an 8-year-old obese dog, resulting in complete healing within four weeks after previous treatments provided only temporary relief.
65 citations
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May 2006 in “Journal of Investigative Dermatology” This study found that dexamethasone significantly reduced ERα mRNA levels and increased aromatase mRNA and activity in cultured human hair follicle dermal papilla cells, suggesting a glucocorticoid-dependent mechanism for estradiol action.
February 1996 in “Clinical Pharmacology & Therapeutics” MK-386 reduces sebum DHT levels.
April 2023 in “JIVA : journal of Indian Veterinary Association Kerala/JIVA :Journal of Indian Veterinary Association, Kerala” This case study reported the successful recovery of a Doberman Pinscher with skin lesions, demodicosis, pyoderma, and malasseziosis following treatment with fluralaner, enrofloxacin, shampoos, immune boosters, and fatty acids.
October 2025 in “Clinical and Experimental Dermatology” In this retrospective study, researchers reported that low-dose oral minoxidil significantly improved hair density in 60 patients with androgenetic alopecia or telogen effluvium over 4-8 months, as detected through standardized AI-powered imaging.
6 citations
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September 2005 in “Expert Opinion on Pharmacotherapy” This review discusses the role of androgens in women's sexual health and highlights the need for further research on androgen replacement therapy to optimize quality of life, but reports no new clinical results.
April 2026 in “Journal of the American Academy of Dermatology” 3 citations
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September 2021 in “JAAD case reports” This review discusses the increased autoimmune events associated with the use of denosumab, a biologic agent for managing postmenopausal osteoporosis and skeletal complications from malignancy, but reports no new data.
October 2024 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in improving treatment outcomes and staying updated on various health conditions.
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February 2024 in “Cosmetics” In this study, researchers developed a novel platform for discovering potential hair loss inhibitors by investigating the testosterone/dihydrotestosterone biosynthetic pathway and its regulation through biochemical mechanisms involving 17β-HSD and 3β-HSD, combined with medicinal plant extracts.
July 2023 in “Veterinary pathology” In this report, the researchers described a follicular dysplastic syndrome in two adult white-tailed deer, where gross alopecia and histologic signs suggestive of alopecia areata were observed, potentially predisposing affected deer to environmental exposure.
June 2013 in “D-Scholarship@Pitt (University of Pittsburgh)” This article discusses the development of an interactive workbook by OCCAM to help cancer patients communicate their use of complementary and alternative medicine with healthcare providers and reports no clinical results.
February 2025 in “Iraqi Journal of Science” This study found that women with polycystic ovary syndrome had significantly higher serum lactate dehydrogenase levels and lower levels of cortisol, dopamine, zinc, and vitamin D3 compared to healthy controls.
This study found that using fenugreek seed extract significantly reduced ovarian volume, cyst size, and prolactin levels in women with PCOS over 12 weeks, with the majority achieving regular menstrual cycles and improved insulin sensitivity.
8 citations
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June 2017 in “Steroids” This study evaluated novel steroid compounds for their ability to inhibit 5α-reductase, showing that compound 16a significantly reduced rat prostate weight more than epristeride and exhibited excellent in vitro inhibitory potency, indicating its potential as a lead candidate for further benign prostatic hyperplasia drug research.
This study found that combining oral minoxidil, oral dutasteride, and dutasteride mesotherapy was the most effective treatment for androgenetic alopecia, with improved outcomes at 12 months and a favorable safety profile, compared to other treatment combinations.
1 citations
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December 2019 in “Current Medicinal Chemistry” This study found that anti-androgens may reduce OCD symptoms, but the evidence is of low quality and further large, randomized trials are needed.
November 2013 in “Journal of clinical & experimental dermatology research” Dutasteride can help treat hair loss in both men and women.
25 citations
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December 2001 in “Expert Opinion on Pharmacotherapy” This review discusses the therapeutic potential of potassium channel openers for various conditions, but notes that their clinical role is not yet fully established.