Search
for
Sort by
Research
240-270 / 1000+ resultsresearch Junctional Epidermolysis Bullosa, Generalized Intermediate Type
research Alopecia and drug eruption of the scalp associated with a new beta-blocker, nadolol.
This report describes a case in which the use of the beta-blocker nadolol was associated with infiltrative dermatitis and significant alopecia, which resolved and resulted in total hair regrowth after discontinuation of the drug.
research Paint brush hair: a case report
This case report describes a man with trichorrhexis nodosa of the beard, who experienced symptomatic improvement after being advised to shave and avoid brushing, confirming the diagnosis.
research Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak
This study reported the expression patterns and potential functions of long non-coding RNAs in the hair follicle cycle of yak, with insights into their sequence conservation between yak and cashmere goat.
research Manganese Ethylene Bis(Maneb)-Induced Degeneration of Hair Follicle Epithelia in the Dosal Skin of WBN/ILA-Ht Rats.
This study found that topical treatment with Maneb led to delayed epithelial cell degeneration in hair follicles of rats due to apoptosis.
research PA33 When bones speak through nails: insights from a paediatric case series
This case series highlighted three pediatric patients with congenital nail anomalies, revealing underlying developmental or genetic issues such as symbrachydactyly and potential Adams–Oliver syndrome, underscoring the critical role of dermatologists in early detection and diagnosis of these conditions.
research Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak
This study reported distinct expression patterns and potential functions of lncRNAs during the hair follicle cycle in yaks, suggesting insights into lncRNA roles and conservation between yak and cashmere goat.
research Intermolecular NH 2 -/Carboxyl-terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity
This study suggests that residues Val-889 and Arg-752 in the androgen receptor's steroid binding domain are crucial for NH2-/carboxyl-terminal interaction, affecting receptor stability and function.
research American Board of Hair Restoration Surgery Celebrates Tenth Anniversary
This address appears to discuss organizations related to hair restoration and surgery but presents no research findings.
research Regulation of itch-induced scratching by nucleus accumbens dopamine receptor-expressing neurons
This study found that distinct neurons in the nucleus accumbens lateral shell regulate scratching behavior differently; D1R neurons promote scratching while D2R neurons help stop it, with elevated dopamine levels during chronic itch potentially enhancing persistent scratching.
research Reviewer #2 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
research A notch above bowl: Specification of niche cells in the Drosophila testis
In this study, researchers investigating the Drosophila testis niche system reported that Notch signaling is crucial for niche cell specification, with early gonadogenesis showing signals coming from outside the gonad to direct cell fate.
research Allogeneic Hair Transplantation with Enhanced Survival by Anti-ICAM-1 Antibody with Short-Term Rapamycin Treatment in Nonhuman Primates
This study found that the MD-3 antibody significantly improved the survival of hair follicle allografts in nonhuman primates by reducing T-cell infiltration.
research Fibroblast Growth Factor 21 is Differentially Expressed in Flank Skin and Regulates the Proliferation of Hair Follicle Cells in Yak
research NAD⁺ Biology in Ageing and Chronic Disease: Mechanisms and Evidence across Skin, Fertility, Osteoarthritis, Hearing and Vision Loss, Gut Health, Cardiovascular–Hepatic Metabolism, Neurological Disorders, and Muscle
This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.
research Expression characteristics of BMP2, BMPR-IA and Noggin in different stages of hair follicle in yak skin
This study found that BMP2 and BMPR-IA inhibited, while Noggin promoted, hair follicle growth in yaks by affecting skin epithelial cell activity.
research Sox9 expression in canine epithelial skin tumors
This study found that Sox9 was variably expressed in most canine skin neoplasms, particularly in those originating from the hair follicle's bulge region, suggesting its potential as a stem cell marker.
research Message of protease nexin-1 is expressed in human dermal papilla cells and is affected by androgen
Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
research Molecular–clinical correlations in a family with variable tissue mitochondrial DNA T8993G mutant load
This study found significant variation in tissue mutant load in individuals with the T8993G mutation, which complicates genetic counseling and may inform genotype-phenotype correlations, especially using hair bulb mtDNA analysis.
research Dual‐Mode Vasodilator M119 Delivery to Hair Follicle via Dissolving Microneedle for Advanced Alopecia Treatment
This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.
research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.
research A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients
This study identified a specific SNP in the CACNB4 gene associated with a higher risk of chemotherapy-induced alopecia in breast cancer patients, which may help develop interventions to improve their quality of life.
research INNOVATIVE THERAPIES IN REGENERATIVE MEDICINE AND TRANSPLANTATION
This pilot clinical study introduces DEC cells as a novel therapy for Duchenne muscular dystrophy, confirming safety and efficacy in seven patients up to 24 months post-treatment.
research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells
This study found that the truncated hHb1-DeltaN transcript in breast cancer cells is produced by a cryptic intron promoter and responds to DNA demethylation, potentially altering cancer cell adhesion.
research Editor's evaluation: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
This study found that in mice, the epidermal microenvironment reverses the oncogenic effects of GNAQQ209L in melanocytes, inhibiting their survival and proliferation through paracrine signals.
research Molecular Analysis of a Series of Israeli Families with Comèl-Netherton Syndrome
This study identified three SPINK5 mutations, including two novel ones, in Israeli patients with Comèl-Netherton syndrome, suggesting recurring mutations that should inform future diagnostic strategies in Israel.
research 057 Single cell RNA and TCR sequencing reveals hyperexpansion of T cell clones and novel regulatory mechanisms of CD8+ T cells in murine alopcecia areata skin and draining lymph nodes
This study found that in mice with alopecia areata, CD8+ T cells showed clonal expansion and specific regulatory networks, which might help identify new therapeutic targets for patients not responding to JAK inhibitors.