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480-510 / 713 resultsresearch Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
![Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis](/images/research/838c4d09-f759-4c8d-a3d2-3f1b7d8354e2/small/13064.jpg)
research Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
research Binding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2
Keratin from hair binds well to gold and BMP-2, useful for bone repair.
![Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration](/images/research/3fccbc1d-a280-4c8f-9498-be64158bdc9d/small/26864.jpg)
research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
![Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study](/images/research/fb47ff10-c66b-4c47-a3ee-b661664c54ab/small/26835.jpg)
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
research Genetic Disorders and Defects in Vitamin D Action
Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
research Quantification of the Vitamin D Receptor-Coregulator Interaction
Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin
sPLA2-IIE is crucial for normal hair follicle structure and skin health.
![The Use of Auto-Antibody Testing in the Evaluation of Interstitial Lung Disease: A Practical Approach for the Pulmonologist](/images/research/1040b2bb-b55a-40c6-ab19-3050e9d2f119/small/14102.jpg)
research The Use of Auto-Antibody Testing in the Evaluation of Interstitial Lung Disease: A Practical Approach for the Pulmonologist
Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and Delta-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
![Endoplasmic Reticulum in Health and Disease: The 12th International Calreticulin Workshop, Delphi, Greece](/images/research/3853e45e-147c-447c-964d-54a8a8d579ce/small/12758.jpg)
research Endoplasmic Reticulum in Health and Disease: The 12th International Calreticulin Workshop, Delphi, Greece
The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.
![Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications](/images/research/7769610f-cf59-4e2b-98b4-ae0049ac7ada/small/19050.jpg)
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium Ascalonicum L.) Extract
![Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2](/images/research/554d079e-ac88-47cf-9f25-1626d37a1c49/small/27751.jpg)
research Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research Enhancing Skin Anti-Aging Through Healthy Lifestyle Factors
Healthy lifestyle changes can significantly improve skin health as you age.
![Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in Non-Mendelian Inheritance-Mediated Feather Growth Rate in Chickens](/images/research/dad59ed5-c073-4cf6-b35b-d743fd79eedd/small/27019.jpg)
research Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in Non-Mendelian Inheritance-Mediated Feather Growth Rate in Chickens
The research found specific genes and proteins that affect how fast chickens' feathers grow, which is not solely determined by traditional inheritance patterns.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
research Rare and Underappreciated Causes of Polycystic Ovarian Syndrome
Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
research Mite Burden and Immunophenotypic Response to Demodex Musculi in Swiss Webster, BALB/c, C57BL/6, and NSG Mice
NSG mice had the most mites, and genetic factors affect immune response and susceptibility.
![Stem Cells Tightly Regulate Dead Cell Clearance to Maintain Tissue Fitness](/images/research/3e840091-e878-4c58-880a-036130745fc7/small/31003.jpg)
research Stem Cells Tightly Regulate Dead Cell Clearance to Maintain Tissue Fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
![Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing](/images/research/2fa28103-2dcc-411e-ab37-26bb4a7a11ac/small/19786.jpg)
research Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing
The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
![Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features](/images/research/0b76f763-7f2b-4e37-acb4-3750334eb05f/small/19783.jpg)
research Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features
Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
![Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling](/images/research/2896904c-9782-4afa-ad2b-e59e182038c1/small/4909.jpg)
research Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling
Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
![Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice](/images/research/2f04ca5d-8249-47f8-bcb1-48af5abd253a/small/19683.jpg)
research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
![Mutations in the Vitamin D Receptor Gene in Four Patients with Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets](/images/research/57d26568-5df9-4e54-a9af-5bd1b0d78037/small/30929.jpg)
research Mutations in the Vitamin D Receptor Gene in Four Patients with Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets
Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.
research Lrig1 Expression in Human Sebaceous Gland Tumors
Lrig1 could be a marker for advanced sebaceous carcinoma.
![All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration](/images/research/f44fbeeb-dbd6-4e10-a41a-73be8a647c81/small/19482.jpg)
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Ectopic Olfactory Receptors in Humans: New Therapeutic Possibilities
Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.