research Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
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research Skin Wounds in the MRL/MPJ Mouse Heal with Scar
MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Finasteride for Female Androgenetic Alopecia
Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
research The Therapeutic Use of Androgens in Women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Minoxidil and the Treatment of Severe Hypertension
Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Four Days of Simulated Shift Work Reduces Insulin Sensitivity in Humans
Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
research MicroRNA Species in Follicular Fluid Associating With Polycystic Ovary Syndrome and Related Intermediary Phenotypes
Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Endogenous Retinoids in the Hair Follicle and Sebaceous Gland
Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
research Health-Related Quality of Life and Psychological Distress in Polycystic Ovary Syndrome: A Hidden Facet in South Asian Women
South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.
research Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study
Botox increased hair count in men with baldness and might work by improving scalp blood flow.
research Estrogens And The Hair Follicle
Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
research The Genetics of Androgenetic Alopecia
Genes and hormones cause hair loss, with four genes contributing equally.
research What Controls Hair Follicle Cycling?
The control system for hair growth cycles is not well understood and needs more research.
research Weekly Docetaxel in Minimally Pretreated Cancer Patients: A Dose-Escalation Study Focused on Feasibility and Cumulative Toxicity of Long-Term Administration
Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.
research Studies of Normal Moult and Artificially Induced Regeneration of Pelage in Peromyscus
Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.
research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Skin fat plays a key role in immune defense and healing beyond just storing energy.
research Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns
Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
research Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance
Thyroid function affects skin health, with a complex interaction between the two.
research Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism
Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice
A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
research A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido
DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.
research Sulphation Catalyzed by the Human Cytosolic Sulphotransferases: Chemical Defense or Molecular Terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis
Trichohyalin is also found in the outer layers of normal human skin.
research The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics
Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Inherited Ichthyosis: Syndromic Forms
Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.