research Desmoglein 4 Is Regulated by Transcription Factors Implicated in Hair Shaft Differentiation
Desmoglein 4 is controlled by specific proteins that affect hair growth.
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research Towards Expansion of Human Hair Follicle Stem Cells In Vitro
Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
research Imaging Nanoscale Changes in Desmosome Protein Organization
Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.
research Individual Variation in Balance Between Platelet-Secreted Growth Factors Causing Contradictory Effects on Hair Follicle Could Potentially Impact Response to PRP Therapy in Patients With Scalp Hair Loss
People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.
research A Novel Animal Model of Desmoglein 1 (Dsg1) Deficiency Reveals an Essential Role for Dsg1 in Epidermal Barrier Formation
Dsg1 is essential for maintaining a healthy skin barrier in mice.
research Stem Cells Sheltered from Air-Raids Repair Airways
Myoepithelial cells can repair airways after severe injury.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research Graham Little-Piccardi-Lassueur Syndrome Associated with Androgen Insensitivity Syndrome (Testicular Feminization)
A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Sox9 Expression in Canine Epithelial Skin Tumors
Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
research Integration of Magnetic Tweezers and Traction Force Microscopy for Exploring the Mechanobiology of Keratinocyte Cell-Cell and Cell-Matrix Anchoring Junctions
The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
research Mutational Landscape of Extramammary Paget Disease
The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research The Metabolic Syndrome-Associated Small G Protein ARL15 Plays a Role in Adipocyte Differentiation and Adiponectin Secretion
ARL15 is important for fat cell development and the release of the hormone adiponectin.
research Human Pilosebaceous Culture
Hair follicle cells can help heal wounds and study skin diseases.
research Two-Photon Microscopy for Intracutaneous Imaging of Stem Cell Activity in Mice
Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
research Developmental Mechanisms Controlling Cell Fate Evolution
The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
research Hair Loss in Autoimmune Cutaneous Bullous Disorders
Hair loss in autoimmune blistering skin diseases varies and may regrow with disease control.
research Rescuing Key Native Traits in Cultured Dermal Papilla Cells for Human Hair Regeneration
Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
research Characterization of X-Linked SNP Genotypic Variation in Globally Distributed Human Populations
The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research Disruption of the Hedgehog Signaling Pathway Contributes to Hair Follicle Cycling Deficiency in VDR Knockout Mice
Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research A Novel Mutation in the MBTPS2 Gene Resulting in Ichthyosis Follicularis, Atrichia, and Photophobia Syndrome
A new mutation in the MBTPS2 gene causes a mild form of IFAP syndrome.
research Retinoic Acid Exerts Sexually Dimorphic Effects on Muscle Energy Metabolism and Function
Retinoic acid affects male and female muscle energy use and function differently.
research Rooster Feathering, Androgenic Alopecia, And Hormone-Dependent Tumor Growth: What Is In Common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling
Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Hair Follicle Stem Cells: In Vitro and In Vivo Neural Differentiation
Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.