Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study concluded that teriflunomide has a consistent and manageable safety profile, with common mild-to-moderate adverse events and no new safety concerns identified over up to 12 years of treatment.

This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.

This study found that low-dose finasteride use in young men was associated with higher reporting of persistent sexual dysfunction, with some cases linked to suicidal ideation.

This study found that securinine and ajmaline significantly inhibited hepatocellular carcinoma cell viability and induced apoptosis, with securinine showing lower toxicity to normal liver cells.

In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

This study found that overexpression of Wnt1a in bone marrow mesenchymal stem cells enhanced mouse hair follicle regeneration and promoted hair cycling.

This article proposes a mechanistic model for how platelet-rich plasma therapy may stimulate hair growth in androgenetic alopecia by promoting vascularization and activating specific signaling pathways, but it reports no new experimental results.

This study found that at least four different human sulfotransferase activities contribute to the sulfation of minoxidil, complicating predictions of individual responses based on ST levels.

This study suggests that finasteride-loaded liquid crystalline nanoparticles could be a viable alternative to oral administration for treating androgenetic alopecia due to their controlled release and skin permeation properties.

This review discusses the roles of immune responses and cells in skin health and disease, emphasizing recent insights into their mechanisms and potential therapeutic applications, but presents no new experimental results.

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

This review discusses the role of miRNA/mRNA regulatory networks in skin development, epidermal homeostasis, and tissue remodeling, and suggests potential for miRNA-based therapies in treating skin conditions, but reports no new clinical results.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

This paper reviews guidelines discussed at a meeting about research and practice themes, but reports no new research findings.

This article presents two cases of keratosis follicularis spinulosa decalvans and reviews its features, highlighting characteristic progression from keratosis pilaris in infancy to cicatricial alopecia in childhood.

This review discusses botulinum toxin's experimental off-label uses in dermatology, highlighting promising results but emphasizing the need for more clinical trials to confirm efficacy and safety.

This case study of a cat with pancreatic carcinoma and paraneoplastic alopecia found that removing the internal tumor reversed hair loss, but symptoms reappeared as the cancer metastasized.

This study found that Transcutol-containing vesicles improved the delivery of minoxidil to deeper skin layers in vitro but did not facilitate its permeation through the skin.

This study found that the aqueous ethanol extract of Myricae Cortex demonstrated in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic effects in mouse and hamster models.

In this study, male rats exposed in utero to low-dose chemical mixtures had permanent reproductive tract alterations, suggesting additive effects even at doses below individual adverse levels.

This study found that progesterone pretreatment in rats potentiated the effect of ethanol on mesocortical dopamine levels, suggesting an influence of neuroactive steroids on ethanol's action.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

This study found that obesity is associated with several skin conditions, such as striae and pseudoacanthosis nigricans, which may serve as markers of excessive weight.

This article reviews the use of cross-sex hormonal therapy in transmen and reports that it is reasonably safe, suggesting monitoring should be frequent initially but can be less frequent over time.

This article reviews factors affecting follicular unit extraction, emphasizing the need to tailor procedures to individual patient characteristics, but reports no new experimental findings.

This abstract provides no results; it is a website notification about cookies and general access to JAMA content.

This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.

This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.

This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.