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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Ozenoxacin 1% cream is an effective and safe treatment for impetigo in children and adults.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Male hormones worsen kidney transplant damage, but blocking them helps.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Wild strawberry waste extract can be a sustainable cosmetic ingredient for treating acne and hair loss.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

Oral alitretinoin is effective for certain types of chronic hand eczema, with mild side effects.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.