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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.

Dutasteride and finasteride affect different cell types differently.

AGA affects many, progresses differently, and early treatment is crucial.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Researchers made two new compounds that could be used for medicine.

Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.

Clomiphene citrate improves fertility in men taking finasteride for hair loss.

Need better hair loss treatments beyond minoxidil, finasteride, and transplants.

Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Oxidative stress affects hair loss in men with androgenetic alopecia.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Finasteride increases hair weight and count in men with hair loss, with best results after four years.

Finasteride increases hair weight and count in men with hair loss.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Diane 35 plus finasteride is more effective for treating hirsutism.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

PRP treatment helps hair growth in most cases, but more research needed.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.