Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that androgen impacted glucocorticoid signaling in the mouse brain only in the prefrontal cortex and substantia nigra, suggesting limited interaction between these hormones at high corticosterone levels.

In this case report from People's College of Medical Sciences, a 20-year-old man initially misdiagnosed with Addison's disease was ultimately found to have strongyloidiasis, with his symptoms and weight loss improving after antihelminthic treatment.

This article reviews androgenetic alopecia in women, highlighting diagnosis criteria and noting that topical minoxidil is currently the only proven treatment for hair growth; it reports no clinical trial findings.

In this study, all stereoisomers of cyoctol were synthesized and tested, revealing that contrary to initial patent claims, cyoctol does not function as an anti-androgen.

The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

This review discusses diagnosis and management strategies for polycystic ovary syndrome in teenagers and reports no new clinical findings, emphasizing tailored approaches considering symptoms, psychological well-being, and fertility needs.

This study found that optimal antioxidant properties of a cream-mask, as indicated by extended Paramecium caudatum motor activity in a toxic environment, were achieved with 10% Sophora japonica tincture and 5% Serenoa repens dry extract.

This study found that Scutellaria baicalensis extract and its main component baicalin inhibited androgen activation signaling and promoted proliferation of human dermal papilla cells, suggesting potential use in treating androgen-associated disorders.

This study found that the effectiveness of 17-beta-estradiol in inhibiting hair growth depends on its application method, and noted significant sex differences in response to 17-alpha-estradiol in male and female mice.

This article provides an overview of recent discoveries about steroidogenic enzymes involved in androgenetic alopecia but reports no new clinical results.

This article reviews the diagnosis and treatment approaches for cutaneous manifestations of PCOS, reporting on various treatment options without presenting new clinical results.

This article states that hormone therapy with estrogens and antiandrogens for transgender females is within an obstetrician-gynecologist's practice scope and involves careful dosing and monitoring to manage short-term thrombotic risks.

This review summarized existing research on finasteride and erectile dysfunction, finding a correlation between finasteride use for benign prostatic hyperplasia and ED, but not strongly for male androgenetic alopecia.

This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.

This review discusses treatment strategies for PCOS, focusing on using insulin-sensitizing medications alongside weight reduction and exercise to improve hyperinsulinemia and hyperandrogenism, and reports no new results.

This review discusses the evolution of scientific understanding and treatment approaches for androgenetic alopecia, from androgen metabolism to the potential of biologic response modifiers, reporting no new clinical findings.

This review discusses investigational treatments for androgenetic and chemotherapy-induced alopecia and reports no new clinical results, highlighting the need for further research.

In this review, the authors discuss various skin conditions linked to hyperandrogenism, such as acne and alopecia, with a focus on androgen-targeted therapies, suggesting these are generally more effective than non-androgen-targeted options.

In a hamster model of COVID-19, this study observed that both low and high doses of testosterone worsened illness in males, while finasteride prevented severe outcomes.

In this study, spironolactone was found to be a safe and effective treatment for acne in women over 25 with abnormal hormone levels, while younger women with normal hormone levels showed less response.

The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.

This study suggests that 9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester from African Yam bean seeds may inhibit the human 5α-reductase II enzyme, potentially helping manage BPH, although further studies are needed.

In this study, dutasteride was found to be effective and safe in treating androgenetic alopecia in men who did not respond to finasteride, with improvements observed in hair loss and quality over 24 weeks.

This review discusses natural remedies and nanoparticle formulations for alopecia management and reports no new clinical results, emphasizing potential benefits of herbal treatments over synthetic therapies.

This study suggests that finasteride's effect on promoting hair growth in men with androgenetic alopecia may be due to its inhibition of 5aR2 localized in hair follicles.

This study demonstrated effective delivery of CRISPR/Cas9 components to dermal papilla cells in androgenic alopecia animals using ultrasound-activated nanoparticles, resulting in specific gene editing and hair growth recovery.

This study suggests that crosstalk between Wnt/β-catenin and TGF-β signaling pathways may contribute to the development of androgenetic alopecia.

This review discusses androgen manipulation strategies for conditions like benign prostatic hyperplasia and prostatic carcinoma but reports no new clinical results.

This study found that a 2-deoxy-D-ribose gel stimulated hair follicle growth in mice with androgenic alopecia, showing effects similar to minoxidil without additional benefits from combining the two treatments.

This animal study found that Cinnamomi cortex water extract reduced prostate weight and improved histological changes in a benign prostatic hyperplasia model, suggesting potential as a treatment.