June 2026 in “Indian Dermatology Online Journal” This study in North India found that patients with alopecia areata have significantly higher levels of coagulation markers, metabolic dysregulation, and systemic inflammation compared to healthy controls, and these factors are linked with disease severity, indicating potential systemic implications beyond localized hair loss.
70 citations
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February 2009 in “Biological Trace Element Research”
3 citations
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January 2020 in “Indian Dermatology Online Journal” In this study, significant correlations were observed between acanthosis nigricans and factors like free testosterone, DHEAS, fasting blood sugar, and BMI, as well as between hirsutism and elevated DHEAS, free testosterone, and BMI among patients with polycystic ovarian disease.
21 citations
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March 2018 in “Experimental Dermatology” This practical guide introduces methods to study human dermal white adipose tissue but does not report new clinical results, emphasizing available techniques and staining protocols.
March 2025 in “AYUSHDHARA” In this study, a 50-year-old woman with symptoms of thyroid dysfunction improved after receiving Ayurvedic treatment with Gandharvahastadi Kwath and lifestyle modifications, which alleviated symptoms like fatigue, muscle cramps, and dry skin, and normalized her TSH levels.
65 citations
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January 2018 in “Nature Reviews Endocrinology” This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.
2 citations
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December 1973 in “Calcified tissue research” This study proposed a hypothesis for cutaneous calcinosis, suggesting that feeding DHT and subsequent epilation lead to ATP release and calcium orthophosphate formation, initiating calcification in rats.
1 citations
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February 2022 in “Indian Journal of Nutrition and Dietetics/Indian journal of nutrition and dietetics” This study reported a significant association between cultural dress practices, reduced sunlight exposure, and symptoms of vitamin D and calcium deficiency among Muslim women in Coimbatore.
March 2019 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers applied Yashtimadhwadi tail using shirodhara and Nasya karma treatments on sixty patients experiencing hair fall, finding that both methods produced excellent results in reducing symptoms such as hair fall, roughness, and dandruff.
33 citations
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October 2005 in “Journal of Investigative Dermatology” A specific gene mutation causes sparse, brittle hair in a family.
13 citations
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July 2012 in “International Journal of Trichology” In this study, the varied phenotype of trichothiodystrophy was highlighted, with findings of distinctive hair shaft abnormalities and a wide range of multisystem issues, including neurologic and urologic disorders.
July 2023 in “Media Dermato Venereologica Indonesiana” In this study, researchers highlighted that in sarcoidosis, macrophages in granulomas can produce vitamin D, potentially leading to calcium imbalances, where vitamin D supplementation may cause hypercalcemia, necessitating careful laboratory assessment before supplementation.
42 citations
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June 2012 in “Clinical and Experimental Dermatology” This study found that 'black dots' seen under trichoscopy are not specific to alopecia areata and may occur in various other hair and scalp conditions.
5 citations
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February 1981 in “Experientia” In this study, a new hairless gene in the Donryu rat strain was identified, showing skin similarities to human skin tumors with multiple follicular cysts.
February 2022 in “International Journal of Complementary & Alternative Medicine” This review explores traditional Ayurvedic methods in Bhela Samhita for assessing health through physical parameters, and calls for further research to validate these practices.
21 citations
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January 2014 in “International Journal of Trichology” This study observed that while dermoscopic features in alopecia areata for dark-skinned individuals align with existing literature, yellow dots appear more frequently and could help in grading disease severity.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes alopecia as a hair loss condition often driven by genetic and androgenic factors, with lifestyle elements like chemical treatments exacerbating the issue; Ayurvedic texts caution against scalp toxins and suggest traditional formulations for support.
July 2022 in “Journal of bio innovation” This article discusses the role of Panchakarma, a set of five Ayurvedic therapies, in detoxifying the body, as described in traditional Ayurvedic texts.
60 citations
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September 2010 in “Journal of the American Academy of Dermatology” Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.
December 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This article discusses the ancient Ayurvedic explanations of premature greying, or Akala Palitya, highlighting how modern lifestyle factors like stress and pollution have increased its prevalence, particularly in urban and developing areas.
July 2017 in “Journal of Ayurveda and Integrated Medical Sciences” This study reported that Ayurvedic treatment involving the internal administration of Vidangarishta, Krimikutararasa, and Shatavari Guda, alongside external papaya exudate application, led to significant, rapid, and lasting improvements in alopecia areata in a week-long trial.
November 2025 in “Veterinary and Animal Science” This study found that both dark and white dromedary camels exhibited high medullation in hair fibers, suggesting adaptations for insulation and heat dissipation in hot desert environments.
August 2026 in “International Journal of Research in Ayurveda and Pharmacy” This review discusses the Ayurvedic concept of Indralupta, resembling alopecia areata, and highlights dietary therapy's potential role in holistic prevention and management, while reporting no new clinical results.
August 2026 in “The Journal of Dermatology” In this review, the authors summarize recent findings on dermal white adipose tissue (dWAT), highlighting its crucial role in the hair follicle microenvironment by regulating inflammation and immune responses, thus influencing hair regeneration.
February 2024 in “Asian journal of medical sciences” This study found that pityriasis capitis was the most common skin disease among 507 hostellers in Pudukottai, followed by acne vulgaris and pediculosis capitis, with factors such as poor hygiene, lack of sunscreen use, junk food intake, and stress contributing to their prevalence.
January 2023 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This article discusses various causes of rickets in children and describes VDDR-2A as a type of refractory rickets often linked to alopecia totalis in infancy, but reports no new clinical findings.
5 citations
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May 2025 in “Nature Communications” This study found that in mice, high-fat diets quickly reduce the skin's ability to transfer heat, while diets preventing obesity increase skin energy loss, suggesting the skin plays an active role in energy metabolism and lipid regulation.
2 citations
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January 2018 in “International Journal of Trichology” This case report describes trichothiodystrophy in two sisters with only hair fragility, illustrating the condition's variable presentation and the importance of regular monitoring for potential associated impairments.
April 2026 in “Annals of Medicine” This study observed that serum 25-hydroxyvitamin D deficiency is significantly associated with Alopecia Areata in a North Indian cohort, particularly among urban residents, suggesting that screening for this deficiency could enhance disease management.
January 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This review compiles references from classical Ayurveda texts on hair health, disorders, and treatments, emphasizing a holistic approach without reporting new clinical results.