May 2024 in “Indian Journal of Pharmacology” In this case report, an 11-year-old girl with alopecia totalis initially treated with minoxidil experienced hypertrichosis, which reversed upon stopping the medication; hair regrowth on the scalp was achieved with tofacitinib after minoxidil discontinuation.
This report describes a complex case of postmenopausal hyperandrogenism with virilization and concurrent rare ovarian tumors, highlighting the critical role of interdisciplinary collaboration in diagnosing and managing such challenging scenarios.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that OR-101, a selective JAK3/TEK inhibitor, was associated with dose-dependent improvements in hair growth in humanized mice with alopecia areata, suggesting its potential as a treatment option.
In this study, a 37-year-old female with resistant hypertension and signs of Cushing's syndrome and primary aldosteronism was found to have normal cortisol levels but high levels of cortisol and aldosterone via adrenal venous sampling, leading to a diagnosis confirmed by right adrenalectomy.
June 2023 in “Scholars journal of medical case reports” This case report describes a 45-year-old Malian woman with Vogt-Koyanagi-Harada disease, highlighting its uncommon occurrence among individuals of African descent and detailing her treatment with prednisone and other adjunct therapies.
June 2023 in “Clinical Chemistry” This case report uncovered that hidden dexamethasone in a dietary supplement caused misleading Cushingoid symptoms and lab results, underscoring the risk of undisclosed ingredients in supplements.
April 2023 in “Journal of Investigative Dermatology” In this study, recombinant type III collagen was found to promote fibroblast proliferation and migration, suggesting potential anti-aging and repairing effects, although it was only effective in significantly inhibiting IL-6, not TNF-α, secretion.
January 2023 in “Health Sciences” The authors concluded that while increased androgens in men may link androgenetic alopecia with severe COVID-19, further research on a larger population is needed to verify this association.
October 2022 in “The American journal of gastroenterology” This case report details a patient with myasthenia gravis and a malignant thymoma whose rising liver function tests, initially thought to be related to antibiotic use, were ultimately attributed to thymoma-associated multiorgan autoimmunity.
August 2022 in “IntechOpen eBooks” This article reviews congenital adrenal hyperplasia, a group of rare genetic disorders affecting steroid synthesis, and highlights the need for specific therapy and ongoing monitoring, but reports no new clinical findings.
December 2021 in “Journal of Rheumatic Diseases” In this case report, a 13-year-old girl with pediatric systemic lupus erythematosus experienced rare ischemic vaso-occlusive retinopathy as a first symptom, and early interventions improved her visual acuity and fever but did not fully restore vision.
May 2021 in “Journal of the Endocrine Society” This case study reports a patient with ACTH-driven cortisol secretion 14 years after adrenalectomy, suggesting possible residual adrenal tissue or extra-adrenal steroid synthesis, challenging the need for lifelong steroid replacement.
April 2020 in “Journal of the Endocrine Society” This case report describes a rare occurrence of giant bilateral adrenal myelolipomas in a 28-year-old female with CAH, emphasizing that large, hormonally active, or painful myelolipomas should be surgically removed.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This study demonstrated that combining amorphization and nanonization of drugs enhances both saturation solubility and dissolution rate, potentially offering therapeutic benefits for formulations like dermal applications.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This study found that dexamethasone-loaded polymeric nanoparticles, particularly those combining ethyl cellulose with Eudragit® RS, may improve controlled release and penetration of corticosteroids into the skin and hair follicles compared to traditional methods.
July 2017 in “Contemporary Endocrinology” This article discusses the ongoing care needs for individuals with 21-hydroxylase deficiency due to mutations in the CYP21A2 gene but does not present new clinical findings.
July 2016 in “Dermatologie pro praxi” This article discusses the use of Espumil foam base in pharmacies for preparing dermatological medications and reports no new clinical results.
June 2016 in “Journal of Coastal Life Medicine” This case report describes a 10-year-old terrier with pituitary-dependent hyperadrenocorticism successfully treated with mitotane.
March 2016 in “Journal of the Turkish-German Gynecological Association” The woman likely has a hormonal imbalance causing excessive hair growth.
January 2016 in “Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver” This study found that novel biodegradable nanocarriers with highly hydrophobic cores significantly increased the solubility and sustained release of hydrophobic drugs and dyes, showing promise for drug delivery applications.
November 2015 in “Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Veterinary Medicine” This article discusses the complexities of diagnosing pituitary dependent hyperadrenocorticism in dogs and reports no new clinical findings, highlighting issues with varied symptoms and episodic hormone secretion complicating diagnosis.
January 2015 in “International Journal of Pharma and Bio Sciences” This review discusses the traditional medicinal uses of Tridax procumbens, attributing its therapeutic properties to various active phytochemicals, but reports no new clinical findings.
April 2014 in “The FASEB Journal” This study found that Geranium Sibiricum L extract may promote hair growth by increasing cell proliferation and migration while modulating cytokine expression in human dermal papilla cells under stress conditions.
January 2014 in “International Journal of Trichology” A man had an unusual type of hair loss that didn't match known patterns and didn't improve with treatment.
December 2011 in “InTech eBooks” This review discusses the potential role of systemic corticosteroids in the treatment of progressive vitiligo, but reports no new clinical results and suggests further research is needed.
July 2010 in “Journal of Investigative Dermatology” Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
January 2008 in “US endocrinology” This paper describes the hGRα gene structure and its expression, focusing on the functional properties of the longest GRα isoform, but reports no new results.
January 2007 in “Journal of The American Academy of Dermatology” Post-steroid panniculitis is now rare because doctors taper steroids more carefully.
January 2007 in “Yearbook of Dermatology and Dermatologic Surgery” Intramuscular triamcinolone and pulse therapy with oral predonine are effective for alopecia areata with manageable side effects, but better relapse prevention is needed.
January 1989 in “Handbook of experimental pharmacology” This review discusses the impact of drugs on human hair growth, highlighting its psychological importance and noting that most contributions are from clinical perspectives, with some input from biochemists and physiologists.