Pituitary-Dependent Hyperadrenocorticism in a Terrier Dog: A Case Report

June 2016 in “ Journal of Coastal Life Medicine ”

Mahdieh Rezaei, Sara Rostami, Mehdi Saberi, Dariush Vosugh

pituitary-dependent hyperadrenocorticism hair loss symmetric alopecia thin skin hyperpigmentation calcinosis cutis dexamethasone suppression test mitotane Cushing's disease Lysodren

TLDR The terrier dog with pituitary-dependent hyperadrenocorticism was successfully treated with mitotane.

A 10-year-old female terrier dog was diagnosed with pituitary-dependent hyperadrenocorticism, presenting symptoms such as polyphagia, weight gain, polyuria, polydipsia, hair loss, and exercise intolerance. Physical examination revealed abdominal distention, symmetric alopecia, thin skin, comedones, bruising, hyperpigmentation, and calcinosis cutis. Laboratory tests indicated stress leukogram, elevated serum alkaline phosphatase, hypercholesterolemia, hypertriglyceridemia, and hyperglycemia. Radiographs showed mild lung patterns and hepatomegaly, while ultrasonography revealed normal-sized adrenal glands. The condition was confirmed with a low-dose dexamethasone suppression test, and the dog was successfully treated with mitotane.

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Pituitary-Dependent Hyperadrenocorticism in a Terrier Dog: A Case Report

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