Post-Steroid Panniculitis: A Lost and Forgotten Entity?

In the document, two cases of post-steroid panniculitis, a rare condition that occurs in children after rapid withdrawal from high doses of steroids, were presented. The first case involved a 13-year-old boy treated with high doses of dexamethasone for a recurrent brain stem glioma, who developed nodules on his jawline one month into steroid tapering. The second case was a 3-year-old boy with nephrotic syndrome who developed erythematous plaques on his cheeks and chin five days after completing a rapid steroid taper. Biopsy confirmed the diagnosis of post-steroid panniculitis, characterized by lobular panniculitis with a mixed infiltrate and "needle-shaped clefts" within adipocytes. The rarity of this condition in recent years is attributed to a better understanding by physicians of the harmful effects of rapidly tapering steroids. The document suggests that post-steroid panniculitis has become less common due to improved steroid tapering practices.