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Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Wnt ligands are crucial for hair growth and repair.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Eclipta alba extract may help hair grow similarly to Minoxidil.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Hair loss gene found on chromosome 3q26.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

HIV can cause unusual and severe skin problems that are hard to treat.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Androgens significantly affect female hair loss, and hormonal treatments may help.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.