Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

This study reports a case where treatment with the TNF alpha inhibitor infliximab successfully resolved refractory alopecia universalis in a 41-year-old woman.

In this study, researchers developed a model using iPS-derived cells to trace and evaluate hair follicle differentiation, which could aid in the development of hair growth treatments.

Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.

Mycophenolic acid may help hair grow by activating pathways important for hair growth.

This study concluded that the expression of specific glycoconjugate terminal sugars is developmentally regulated during rat hair follicle morphogenesis.

This study found that murine epidermal stem cells implanted subcutaneously in a biodegradable carrier could survive and differentiate into structures resembling native dermis without significant rejection in recipient mice.

In this study, researchers discovered that the interaction between the hairless protein and the wise protein is crucial for hair-follicle regeneration, helping bald mice regrow fur.

This study suggests that the interaction between the hairless and wise proteins can help bald mice regrow fur, highlighting its essential role in hair-follicle regeneration.

This study established a pluripotent stem cell line from a patient with androgenetic alopecia, which can potentially be used to study the disease's pathological mechanisms.

This article explores the effects of DHT on hair follicle miniaturization and finasteride's role in preventing this process, without presenting new clinical data.

This review discusses keratin disorders and potential RNA interference therapeutics, reporting no new clinical findings but highlighting the promise of siRNA for future treatments.

This review discusses the hair follicle cycle's complex regulation and highlights the potential for targeting catagen control in future therapies without presenting new experimental data.

This paper reviews keratoacanthoma as a tumor that resembles but rarely progresses to squamous cell carcinoma, detailing its stages, potential origins, and distinguishing features from other similar growths, without reporting new clinical results.

This study found that in a transgenic mouse model, β-HPV infection led to increased skin thickness and proliferation of specific keratinocyte stem cells, which may contribute to squamous cell carcinoma development.

This review discusses recent advances in understanding Merkel cell carcinoma biology, including the development of genetically-engineered mouse models and potential therapeutic targets, but reports no new clinical results.

This review discusses recent advancements in using macromolecules for hair loss treatment, highlighting microneedle and nanoparticle delivery systems, tissue-engineered scaffolds for hair follicle regeneration, and artificial skin platforms as drug screening methods.

This study by Flores and colleagues found that the type of tumor that develops in a specific subset of epidermal stem cells is influenced by which tumor suppressor gene is deleted.

Researchers found a new genetic mutation causing a rare hair loss condition in the first Japanese child studied.

In a rat skin wound model, this study observed that a composite dressing using chitosan hydrogel and exosomes derived from adipose mesenchymal stem cells enhanced wound healing by promoting collagen deposition, angiogenesis, and regeneration of hair follicle structures.

This report from the seventh AA Research Summit discusses research highlights and sets future priorities for managing alopecia areata.

This review discusses recent advancements in understanding how the extracellular matrix regulates epidermal stem cell fate and highlights the significance of ECM in stem cell maintenance and differentiation, with implications for regenerative medicine.

This guide explores the fundamental science and practical applications of nanocrystal technologies to enhance the bioavailability of poorly water-soluble drugs, detailing synthesis methods, stability solutions, and drug delivery innovations like hydrogel composites and microneedle platforms.

This comprehensive guide from nanotechsci.com explores how nanocrystal technology enhances the bioavailability of poorly water-soluble pharmaceuticals, detailing the science behind crystallization and practical synthesis techniques, and discussing their advanced drug delivery applications across various routes.

Using mouse hair follicle organoids, this study demonstrated that BMP4 plays a key role in controlling hair follicle coloration and growth, as well as directing Nestin-positive stem cells towards becoming melanocytes, the pigment-producing cells responsible for hair color.

In this study, researchers observed that spontaneously mutated mice with a hair loss phenotype exhibited significant differential expression of genes related to keratinization and hair follicle formation, suggesting these mice could model human alopecia for future research and treatment development.

In this study using a mouse model, researchers found that expressing Lef1 in dermal fibroblasts may enhance skin regeneration without affecting normal development.

This source provides no abstract, offering no results or conclusions on a case involving a 14-year-old boy with abrupt-onset hair changes presented in a photo quiz format in Pediatric Dermatology.

This article discusses the roles of retinoic acid in cellular differentiation and its side effects like hair loss, but reports no new clinical findings.

This article explores the details of hair growth but reports no new research findings.