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The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

A male with aromatase deficiency improved bone health with estradiol treatment.

No true link between AGA and insulin resistance, but coexistence may worsen AGA.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

Immune cells affect hair growth and could lead to new hair loss treatments.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Using neurohormones to control keratin can lead to new skin disease treatments.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Women with PCOS have more emotional and body image issues than healthy women.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Some skin lymphomas can look like common skin issues and need careful testing to diagnose correctly.

Early balding at 40 increases prostate cancer risk.

Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

A patient with Rhupus was diagnosed with Rowell syndrome and treated with various medications.

Scientists made a mouse that can be made to lose hair and then grow it back.

Some alternative therapies for vitiligo show promise but need more research.

Many research paper titles in dermatology journals lack scientific precision.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Hair loss caused by longer latent hair cycle and sudden miniaturization, not gradual follicle size reduction.

PRP helps with skin, hair, and wound treatments but needs more research for standard use.

Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.