Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the expanding applications of dermoscopy in dermatological diagnosis beyond its initial use for detecting dysplastic nevi and reports no new clinical results.

This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

This study aims to determine if an integrated early childhood development package can reduce developmental delays among two-year-old children in public health centers in Pakistan.

This study highlights the phenotypic variability in 5 patients with Woodhouse-Sakati syndrome carrying the c.436delC mutation, suggesting a broader range of clinical presentations than previously recognized.

This article outlines opportunities for academic growth provided by the Indian Association of Dermatologists, Venereologists, and Leprologists, reporting no new research findings.

This abstract highlights that preliminary results from the REDUCE trial indicate dutasteride may lower prostate cancer incidence by 23% in older men compared to a placebo.

This article reviews advancements in carbon dots for tissue engineering and regenerative medicine, highlighting challenges and future directions without presenting new clinical findings.

This study found that the novel dermal cooling system was an effective and safe treatment for reducing pigmentation in benign pigmented lesions in Asian patients, with minimal side effects.

In this study, the vitamin D analogues 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol were found to thin the living cell layer and affect differentiation marker expression in organotypic cultures of human outer root sheath cells.

This study found that exosomes derived from dermal papilla cells can enhance the proliferation of hair follicle stem cells by stimulating the LEF1 pathway, offering insights into hair follicle growth regulation.

In this study, the researchers found that using a core-shell assembly of adipose-derived stem cells and dermal papilla cells reconstructed hair follicle cellular arrangements more effectively than mixed assemblies, enhancing hair formation in vivo.

This study identified histologic lesions and a defect in adhesion molecules causing hair loss in mice with the bal mutation, linked to a mutation in the desmoglein 3 gene.

This study developed new immortalized keratinocyte cell lines lacking COL7A1 using CRISPR/Cas9 technology, providing a valuable model to explore the biology and treatment options for recessive dystrophic epidermolysis bullosa.

This study developed a new measurement procedure using isotope dilution-liquid chromatography-tandem mass spectrometry for accurate quantification of DHEAS in human serum or plasma, demonstrating high selectivity, sensitivity, and low measurement uncertainty, making it suitable for routine standardization and clinical evaluation.

This letter to the editor discusses the potential exacerbation of discoid lupus erythematosus by radiation therapy and reports no new clinical findings.

This study investigated the mechanism responsible for pili torti formation in Björnstad syndrome using a transmission electron microscope, but did not establish a definitive explanation.

This article discusses the advantages and different techniques of dermoscopy for skin lesion visualization and reviewing no new clinical results; it emphasizes the integration of polarized light and the importance of training.

This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.

In this study, researchers found that a specific genetic variant in the INSR gene is linked to severe insulin resistance and hyperandrogenemia in type A insulin resistance syndrome, suggesting the benefit of exon sequencing for accurate diagnosis and treatment.

This study reports on an ongoing Phase I/IIa clinical trial of ex vivo gene therapy for treating severe Recessive Dystrophic Epidermolysis Bullosa, involving six adult participants with COL7A1 mutations resulting in deficient type VII collagen production.

This study found that nano-sized lipid particles improved the skin accumulation and retention of dexamethasone compared to a base cream, suggesting potential benefits for inflammatory skin disease treatment.

This announcement from Redfield Corporation introduces the first disposable linear slot punches for hair restoration surgery, with sharpness guaranteed for up to 500 recipient sites.

This study identified two distinct VDR gene mutations among Lebanese families with hereditary vitamin D-resistant rickets, noting varied treatment responses and promising outcomes despite severe phenotypes.

This abstract discusses two types of hereditary vitamin D metabolism defects, VDDR I and VDDR II, and reports on their distinct characteristics and treatment responses, without presenting new clinical data.

This Delphi survey study identified six key domains that should be measured in all future psoriasis clinical trials to ensure comprehensive assessment, including skin manifestations and treatment satisfaction.

This study reviewed the genetic and phenotypic aspects of Olmsted syndrome, highlighting pathogenic mutations in TRPV3 and MBTPS2 genes and their association with specific skin manifestations like symmetrical keratoderma and hyperkeratotic plaques.

This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.

This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.

This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.

In this study, CRISPR/Cas9-engineered Arabidopsis mutants revealed diverse functional differences among expansin proteins essential for root hair growth, highlighting variability in protein trafficking, cell wall binding, and evolutionary changes in critical residues affecting wall loosening.