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In this study, overexpression of ornithine decarboxylase accelerated basal cell carcinoma in Ptch1+/– mice under UVB exposure, while its inhibition reduced tumor induction, suggesting potential chemoprevention strategies in humans.

This study found that the DNN-DTIs prediction model achieved high accuracy in predicting drug-target interactions, suggesting its potential application in drug repositioning and the discovery of new uses for existing drugs.

In this case study, trichoscopy was found to be a valuable non-invasive tool for diagnosing dissecting cellulitis of the scalp, enabling early detection and intervention to prevent disease progression and reduce the need for invasive procedures.

This report examines the mechanisms by which TCDD affects human epidermal and carcinoma cells, aiming to create a risk assessment model for halogenated aromatic compounds, but presents no new clinical results.

DACC-based dressings are more effective than silver-based ones for treating chronic wounds with antimicrobial resistance.

This study found that visual hair density is better correlated with hair count and shaft diameter, leading to the development of the Hair Diameter Index used in planning hair restoration procedures.

This study found that after 24 weeks of DPCP treatment for alopecia areata, there was a significant increase in new capillaries and hair regrowth detectable by videocapillaroscopy.

This study found that dysregulation of the DNA damage response in stem cells is a common factor of aging, affecting tissues like the skin, brain, kidneys, and intestine.

This study found that using an LED array with an 863 nm wavelength delayed tumor development and reduced systemic inflammatory cytokines in DMBA/TPA-induced mouse skin tumors, suggesting potential but limited benefits of light therapy.

This proof-of-concept study reported that a new, ultra-fast, one-step immunohistochemistry method improved the interpretation of Mohs surgery slides, particularly for poorly differentiated tumors.

This study suggests that central centrifugal cicatricial alopecia may involve a CD4-predominant T-cell process with potential PD1/PDL1 pathway involvement, indicated by increased caspase 3 expression and loss of PDL1.

This study found that finasteride's solubility and bioavailability were improved when using a dimethyl-β-cyclodextrin inclusion complex compared to the drug alone.

This pilot study found that night shift workers showed fewer signs of wrinkle formation compared to day workers, but there were no significant differences in DNA amplification or collagen percentage.

This study concludes that the Greek version of the Dysmorphic Concern Questionnaire is a reliable and valid tool for assessing body dysmorphic disorder-related concerns in both research and clinical settings.

In this study, researchers identified the antimicrobial peptide dermcidin in sebocyte lipid droplets, challenging the previous understanding of dermcidin as exclusively sweat-specific.

This study observed that dalpiciclib is associated with fewer adverse events like diarrhea and hepatotoxicity compared to other CDK4/6 inhibitors, potentially offering better patient-perceived safety and quality of life.

This study found that diphenylcyclopropenone (DPCP) was more effective and better tolerated than dinitrochlorobenzene (DNCB) in promoting hair regrowth in patients with alopecia areata.

This report describes a neurometabolic disorder linked to gain-of-function variants in the ODC1 gene, characterized by developmental delay, ectodermal abnormalities, and notable facial and neuroimaging features.

This commentary discusses ethical concerns with direct-to-consumer teledermatology services, highlighting potential conflicts of interest and issues with care quality.

This study found that using ionic liquid for specimen preparation allowed for observation of dermal papilla cells and their cilia in near-living conditions, reducing damage typically caused by conventional preparation methods.

This case report describes a 32-month-old girl with a newly identified pediatric disorder linked to a de novo mutation in the ODC1 gene, mirroring symptoms seen in a transgenic mouse model.

This study evaluated a new AI-linked imaging device for grading dandruff severity, finding high correlation with expert assessments and suggesting its potential application in other skincare areas due to its versatility and ease of use.

In this study, TCDD administered to male rats down-regulated EGF receptor in liver plasma membranes and increased protein kinase activity, suggesting EGF receptor–mediated toxicological effects.

This study found that inhibiting the enzyme ornithine decarboxylase (ODC) prevented UVB-induced basal cell carcinomas in a mouse model, suggesting ODC is a potential target for chemoprevention strategies.

This study found that digital droplet PCR (ddPCR) outperformed qPCR in detecting replication competent lentivirus in CAR-T products by offering better sensitivity, specificity, and reproducibility, making it a reliable and rapid method for ensuring patient safety.

In this study, reflectance confocal microscopy was used to diagnose periorificial dermatitis, revealing specific skin changes such as hair follicle dilatation, increased vascular density, and inflammation, which help distinguish it from similar conditions.

This study highlights that dissecting cellulitis of the scalp affects a diverse racial population and is associated with male sex, metabolic dysfunction, and psychiatric comorbidities, challenging its traditional characterization as primarily a disorder of Black men.

The ILDS Newsletter reported on efforts to support albinism patients in Tanzania and dermatological conferences.

This study concluded that there was clear evidence of carcinogenic activity of C.I. Acid Orange 3 in female F344/N rats but not in male rats or B6C3F1 mice of either sex.

In this report, a 19-year-old Japanese man experienced severe and prolonged urticarial reactions following treatment with diphenylcyclopropenone for alopecia universalis, emphasizing the need for caution with potent sensitizers.