3 citations
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January 2008 in “Journal of the American Academy of Dermatology” A patient's skin rash did not affect the area where a previous viral rash was healing, suggesting a rare immune response.
1 citations
,
September 2024 in “Journal of the American Academy of Dermatology” Farudodstat may effectively treat alopecia areata without harmful side effects.
8 citations
,
October 2019 in “The Journal of surgical research/Journal of surgical research” This study demonstrated that sodium valproate accelerates skin healing and reduces necrosis in a rat model of skin flap potentially through mechanisms involving GABA and histone deacetylase pathways.
August 2018 in “Online journal of neurology and brain disorders” This study reported that sodium valproate completely stopped epilepsy in 43% of patients and reduced seizures by 50% in 22% of patients who were resistant to other anticonvulsants.
April 2025 in “Suez Canal University Medical Journal” This case report details a 66-year-old male patient who developed eosinophilic pleuro-pericardial effusion likely due to valproic acid toxicity or overdosage, with full recovery observed after medication adjustments at a six-month follow-up.
2 citations
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June 2024 in “International Journal of Drug Delivery Technology” This review describes advanced drug delivery systems for dithranol aimed at overcoming stability issues and skin irritation seen in conventional formulations, highlighting options like nanoparticles and liposomes for improved psoriasis treatment.
12 citations
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September 2014 in “Bone” This study characterized two siblings with hereditary vitamin D resistant rickets and a mutation in the vitamin D receptor, finding no immune-related disorders despite a defective T cell response to vitamin D.
24 citations
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November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” In this study, mutations in the vitamin D receptor were identified in Brazilian children with rickets and alopecia, leading to impaired receptor activation and reduced 24-hydroxylase expression.
4 citations
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October 2015 in “JAAD Case Reports” This case report describes a patient experiencing nail nonadherence due to sterile matrix scarring associated with valproic acid use, and suggests nail bed excision with sterile matrix grafting as a potential surgical solution.
19 citations
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February 2001 in “Journal of paediatrics and child health” This report documents a 14-year-old Chinese boy with mitochondrial encephalopathy, lactic acidosis, stroke-like episodes, and a de novo A3243G mitochondrial DNA mutation, highlighting the condition's multisystem involvement without ragged red fibers in muscle biopsy.
This study found that both levetiracetam and valproate sodium effectively reduced seizure frequency and duration in patients with refractory epilepsy, but levetiracetam had fewer side effects related to liver enzyme changes.
1 citations
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June 2018 in “JAMA Dermatology” This abstract does not contain specific research findings or results, but instead provides information related to the JAMA Dermatology journal's online platform and services.
3 citations
,
January 1992 in “Clinical Pediatric Endocrinology” This study observed wide clinical diversity among five patients with the same VDR gene mutation causing vitamin D-dependent rickets type II, suggesting involvement of a nuclear accessory factor and a nongenomic action of the vitamin.
September 2018 in “Practical diabetes” This review indicates that sodium valproate might benefit diabetic peripheral neuropathy patients, but evidence is limited and inconsistent, so it should be reserved for treatment-resistant cases.
January 2016 in “Zurich Open Repository and Archive (University of Zurich)” This study concludes that dietary L-serine supplementation shows promise as a long-term therapy for hereditary sensory and autonomic neuropathy type 1, reducing neurotoxic 1-deoxysphingolipid levels and improving symptoms in severe cases.
21 citations
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January 2006 in “Hormone Research in Paediatrics” In this case study, a girl with hereditary vitamin D resistant rickets had a novel mutation in the VDR gene that affected hair cycling without causing total alopecia, suggesting ligand-independent VDR function in hair cycling.
151 citations
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June 2010 in “Endocrinology and metabolism clinics of North America” This article compares two rare genetic diseases, vitamin D-dependent rickets type 1 and type 2, focusing on their similar presentations of hypocalcemia and rickets in infancy, but reports no new clinical results.
April 2023 in “Journal of Investigative Dermatology” This study found variation in erythema induction across skin types, suggesting different SSR dose responses and highlighting a potential model for tailoring anti-inflammatory treatments.
3 citations
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September 2022 in “Archives of dermatological research” In this study, fractional CO2 laser treatment for alopecia areata was found to significantly increase terminal hair and patient satisfaction compared to betamethasone valerate cream alone, highlighting its efficacy and safety both as a standalone and combined treatment.
1 citations
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October 2023 in “Journal of clinical psychopharmacology” In this case report, a young male developed bilateral pleural effusion and persistent fever after starting divalproex sodium for bipolar disorder, which improved upon discontinuation of the drug, suggesting a possible link between divalproex sodium and pleural effusion.
2 citations
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September 2021 in “Human Psychopharmacology: Clinical and Experimental” This review discusses valproate-associated hair abnormalities, describing their common and benign nature, and outlines management strategies, though new clinical results are not provided.
1 citations
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January 2024 in “Pediatric Endocrinology Diabetes and Metabolism” In this retrospective study of eight Saudi children with hereditary vitamin D resistant rickets, researchers observed that adjunctive cinacalcet appeared safe and showed initial promise in improving serum PTH levels, though further investigation is needed to confirm its efficacy.
17 citations
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April 2004 in “Acta Clinica Belgica” This study found that ultraviolet light-enhanced visualization can detect subtle skin changes linked to carotene and vitamin A deficiency, which improved with dietary correction in deficient individuals.
5 citations
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July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” This study described the clinical and genetic features of two Iranian siblings with hereditary vitamin D resistant rickets, identifying a specific VDR gene mutation contributing to their symptoms.
April 2024 in “Journal of environmental management” This study investigated the electron transfer processes in an iron-mediated DAMO–anammox system, finding that Fe3+ accelerated c-type cytochrome-mediated electron transfer and suggested that riboflavin acts as an electron shuttle and DIET may occur among these microorganisms.
May 2026 in “Journal of Medicinal Chemistry” In this study, the authors developed a novel PROTAC named dAR-6–1, which demonstrated superior hair regeneration in an AGA mouse model compared to minoxidil, highlighting its promise as a therapy due to potent AR degradation and excellent skin permeability.
December 2025 in “Medical dosimetry”
13 citations
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October 2010 in “Seizure” This study reported that extended-release valproate significantly reduced seizure frequency and improved quality of life in epilepsy patients over six months, despite some adverse effects like weight gain and tremor.
1 citations
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August 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses detoxification methods for poisonous plants in Ayurvedic medicine, detailing purification techniques and their pharmacological effects, but it reports no new results.
12 citations
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June 2016 in “Clinical and experimental dermatology” This study reported a previously undescribed G573V point mutation in the TRPV3 gene as a cause of familial Olmsted syndrome in a Mongolian family.