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This study found that Danthron induced apoptosis in a human malignant melanoma cell line through mitochondrial, endoplasmic reticulum, and death receptor pathways.

This review discusses the cosmetic use and safety of Hypericum Perforatum Extract and Oil, finding that current data are insufficient to support their safety in formulations due to a lack of comprehensive testing.

This article discusses the long-standing use and safety of opioids in anaesthesia, noting that respiratory depression is a manageable side effect due to the availability of opioid antagonists.

In this review, the researchers compared the traditional use of Senna Makki in Unani medicine for various ailments to modern pharmacological evidence, endorsing its role as a laxative but indicating further research is needed for its efficacy in other therapeutic areas.

This article discusses how medicinal plants, known for their antiviral, immunomodulatory, antioxidant, and anti-inflammatory properties, may help alleviate long-term COVID-19 effects, but emphasizes the need for further clinical trials to confirm safety and efficacy.

This article reviews anthralin's pharmacology, mode of action, and its use for psoriasis and other dermatoses, but reports no new clinical results.

This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.

This article discusses the structure and protective function of pangolin scales, emphasizing their composition of α-keratins and β-keratins, and highlights evolutionary keratin diversification in tetrapods; it reports no new empirical findings.

In this study of Danioninae species, researchers reported that the presence of breeding tubercles on the pectoral fins is conserved in certain species and linked to local androgen conversion, with steroid 5-α-reductase playing a crucial role in their development.

This review describes advanced drug delivery systems for dithranol aimed at overcoming stability issues and skin irritation seen in conventional formulations, highlighting options like nanoparticles and liposomes for improved psoriasis treatment.

In this study, researchers successfully synthesized a rigid 3a-arylhexahydropentalene-1,6-dione from the easily accessible starting material cyclopent-2-en-1-one, highlighting a structural motif common in natural products and pharmaceuticals.

This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.

This study shows that microdiffraction experiments reveal structural layers in keratinous tissues, each with different keratin types, potentially explaining their dual role as mechanical support and chemical barriers.

This study demonstrates a varied distribution of keratins in the epidermis of the Malayan pangolin, suggesting evolutionary adaptations related to their distinctive scales.

This study suggests that stimulating olfactory receptors in human hair follicles with Sandalore® increases antimicrobial activity by upregulating dermcidin production, potentially offering a novel approach for treating hair follicle diseases with bacterial issues.

This study formulated and characterized a dutasteride-loaded nanocrystalline suspension for long-acting parenteral delivery, finding that it provided sustained drug release in rats with a significant reduction in local inflammation over 28 days following intramuscular injection.

This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.

This study is the first to document significant age-related pathologies in endangered captive Julia Creek dunnarts, highlighting hormonal dysregulation and reproductive issues in females, while males exhibited higher occurrences of cutaneous diseases and testicular degeneration, providing valuable insight for conservation efforts.

This study found that the structure and mineral content of dromedary camel hair, specifically the medulla patterns, medulla index, and elemental composition, change with age, revealing differences among camels aged 1 year, 3-5 years, and 8-10 years.

In this study, researchers found a correlation between x-ray patterns and the element composition of human hair, with certain metal roles in the hair matrix considered.

In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.

This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.

This study presents the first detailed 3D models of the complete K1/K10 keratin dimer and identifies structural features and interactions that may inform understanding of keratin filament assembly.

This case report indicates that trichoscopy may significantly improve the diagnosis of Netherton syndrome by noninvasively identifying typical hair abnormalities without the need to pull hair.

This report describes two patients with ichthyosis linearis circumflexa exhibiting symptoms resembling Netherton's disease, noting multiple hair shaft defects and discussing a possible connection to aminoaciduria.

This study found that intracutaneous injections of nandrolone phenylpropionate specifically induced local epidermal thickening and increased sebaceous gland volume in female hairless hamsters, independent of a dermal inflammatory response.

In this case study, a 15-year-old obese boy was diagnosed with acanthosis nigricans and hair casts in the axillae, with Wood's lamp and dermoscopic examination revealing specific features, yet fungal infection was ruled out through a negative KOH test.

In this case report, a 6-year-old boy with Netherton syndrome was diagnosed using trichoscopy, which revealed characteristic hair shaft abnormalities such as bamboo, golf tee, and matchstick hairs.