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30-60 / 1000+ resultsresearch [Protective effect of lactalbumin-bound vitamin D2 on hair epilation caused by medicinal drugs].
research Histoire du th\'eor\`eme de Jordan de la d\'ecomposition matricielle (1870-1930)
This study describes a follicular automaton model that simulates human hair cycles and may replicate hair pattern evolution seen in diffuse or androgenetic alopecia.
research A use-and-transformation model for evaluating public R&D: Illustrations from polycystic ovarian syndrome (PCOS) research
This article presents a model for evaluating public R&D that emphasizes measuring capacity-based metrics over traditional outcome-based metrics, using the concept of a Knowledge Value Collective.
research Invasive Aspergillosis in a patient with Asthma post H1N1 PneumoniaD Nayar1, Cook P1, Lim L1, Allison D1, Denning D2County Durham and Darlington Foundation Trust1National Aspergillosis Centre, University Hospital of South Manchester2
This case study presents an asthma patient with H1N1 pneumonia who developed invasive Aspergillosis despite avoiding steroids, suggesting that factors other than steroid use can contribute to IA in such patients.
research Determining the Relationship Among Cattle Genotype, Hair Coat Score, and Productivity Through the Investigation of Single Nucleotide Polymorphisms within Prolactin, Dopamine Receptor D2, and Melatonin Receptor 1A
research The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating
This study suggests that the 5α-reductase inhibitor finasteride modulates sensorimotor gating in rats by affecting D1 and D3 receptors, but not D2 receptors, with varying effects based on genetic strain.
research Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice
This study found that dutasteride may offer neuroprotection in early-stage Parkinson's disease by preventing loss of striatal dopamine and altering steroid levels in MPTP-lesioned mice.
research The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson’s disease
This study found that finasteride significantly reduced levodopa-induced dyskinesia in both male and female rats without diminishing l-DOPA's motor benefits, indicating potential for clinical trials in Parkinson's patients.
research Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors
This study found that male 5α-reductase 2 knockout mice showed deficits in social dominance behaviors and reduced dopamine receptor binding in a brain region related to social ranking.
research Water distribution in human hair microstructure elucidated by spin contrast variation small-angle neutron scattering
This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.
research Change in Hair Cycle and Hair Length in Nude Mice by Administration of Deuterium Oxide
This study suggests that D2O increases hair length in nude mice by extending the hair cycle duration, particularly the hair-existing phase, which is associated with increased mast cell density.
research Diabetex: A novel approach for diabetic wound healing
This study found that Diabetex significantly improved wound healing and reduced fasting blood sugar in diabetic rats, showing potential as a safe and economic treatment strategy for diabetic-resistant wounds.
research A young male of hemorrhagic cerebral infarction associated with finasteride and minoxidil
This case study describes a 21-year-old man who experienced a hemorrhagic stroke potentially linked to finasteride and minoxidil use for androgenic alopecia, emphasizing the need for thorough medication history in young stroke patients.
research Wound Healing and Skin Regeneration
This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.
research Recent advances in electrospun nanofibers for wound healing
This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.
research Rickets with alopecia: An inborn error of vitaminD metabolism
This report describes two sisters with rickets and alopecia unresponsive to high doses of vitamin D2, where oral phosphorus supplements led to significant clinical improvement.
research Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?
This study found that low serum ferritin and vitamin D2 levels are associated with hair loss in females with chronic telogen effluvium and female pattern hair loss, suggesting potential benefits of screening and supplementation.
research Does prostaglandin D2 hold the cure to male pattern baldness?
This review discusses the role of Prostaglandin D2 and its synthase in androgenetic alopecia but reports no new clinical findings, suggesting pathways for future therapeutic development.
research Mechanism of action of herbs and their active constituents used in hair loss treatment
This article reviews mechanisms by which herbal ingredients may stimulate or inhibit hair growth, and it reports no new clinical findings while suggesting potential for developing hair loss treatments.
research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.
research New drugs under investigation for the treatment of alopecias
This review explored the new and emerging treatments for androgenetic alopecia and alopecia areata, finding that JAK inhibitors show promise for alopecia areata, while advancements in stem-cell research may eventually lead to new and improved treatments for androgenetic alopecia.
research Genetic and molecular aspects of androgenetic alopecia
This review discusses advances in molecular biology and genetics related to androgenetic alopecia and reports no new clinical results.
research The therapeutic potential of CRTH2/DP2 beyond allergy and asthma
This review discusses the potential roles of prostaglandin D2 and its receptor CRTH2 in various diseases beyond allergies and asthma and reports no new clinical results.
research A preliminary study on topical cetirizine in the therapeutic management of androgenetic alopecia
This study found that topical cetirizine 1% significantly improved hair density and diameter in patients with androgenetic alopecia, with patients tolerating the treatment well.
research Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase
This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.
research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D2 synthase expression in adult rats
This study found that low doses of bisphenol A may increase proliferation of the ventral prostate in adult rats by altering the estrogen to androgen ratio and gene expression.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review
This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.
research Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer
This article discusses the hypothesis that mechanisms driving androgenic alopecia may reduce the risk and proliferation of prostate cancer by increasing prostaglandin D2 levels but presents no new clinical findings.
research A new target for squamous cell skin cancer?
This study suggests that AKR1C3 expression may influence PGD2-related pathways in skin squamous cell carcinoma and potentially be involved in androgenetic alopecia, although further investigation is needed to clarify its role.