Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
45 citations,
September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
1 citations,
January 2005 in “Side effects of drugs annual” The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.
2 citations,
December 2013 in “Xenobiotica” Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
7 citations,
March 2011 in “Expert Opinion on Drug Safety” Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
January 2016 in “Springer eBooks” Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.
65 citations,
January 2005 in “American journal of clinical dermatology” Children with scalp fungal infections need proper diagnosis and treatment, usually with antifungal medications, and newer drugs may offer quicker recovery.
19 citations,
January 2012 in “International Journal of Trichology” Propionibacterium acnes might be linked to hair casts and possibly alopecia.
11 citations,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
1 citations,
January 2010 in “Serbian Journal of Dermatology and Venereology” The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.
October 2015 in “Elsevier eBooks” Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
25 citations,
October 2015 in “Dermatology” Dapsone improved pustular psoriasis in patients who didn't respond to other treatments and is considered a well-tolerated option.
January 2019 in “ARC journal of pharmaceutical sciences” Acne can be managed with various treatments and requires psychological support due to its emotional impact.
31 citations,
January 2017 in “Phytotherapy Research” Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
20 citations,
April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
1 citations,
February 2017 in “Journal of gynecology and womens health” The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
54 citations,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin A affects hair loss and immune response in alopecia areata.
61 citations,
April 2018 in “Frontiers in endocrinology” Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.
November 2024 in “Frontiers in Endocrinology” Hair analysis can help diagnose adrenal disorders non-invasively.
7 citations,
December 2019 in “Pharmaceutics” Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.
February 2024 in “Brain research bulletin” Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
54 citations,
October 2019 in “Cochrane library” Some drugs may reduce prostatitis symptoms short-term with few side effects.
156 citations,
October 1996 in “Science of The Total Environment” Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.
70 citations,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
21 citations,
January 2003 in “Skin pharmacology and physiology” Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
171 citations,
October 1990 in “Alcoholism/Alcoholism, clinical and experimental research” The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
77 citations,
April 2009 in “British Journal of Dermatology” Aromatase gene variation may increase female hair loss risk.
19 citations,
June 2002 in “American Journal of Dermatopathology” Apoptosis contributes to hair loss in androgenetic alopecia.
13 citations,
January 1995 in “Postgraduate medicine” Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.