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480-510 / 1000+ results![Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy](/images/research/7cf2daf0-fa3e-4643-9811-6c70bc66855d/small/29837.jpg)
research Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy
The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.
research Dissecting the Impact of Chemotherapy on the Human Hair Follicle
Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
research Peripheral Arterial Disease: Diagnosis and Management
Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.
![NEONATAL INHIBITION OF ANDROGEN ACTIVITY ALTERS THE PROGRAMMING OF BODY WEIGHT AND OREXINERGIC PEPTIDES DIFFERENTIALLY IN MALE AND FEMALE RATS](/images/research/5aeea9a7-7fa0-40b8-abfa-a53d45782866/small/31680.jpg)
research NEONATAL INHIBITION OF ANDROGEN ACTIVITY ALTERS THE PROGRAMMING OF BODY WEIGHT AND OREXINERGIC PEPTIDES DIFFERENTIALLY IN MALE AND FEMALE RATS
Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
![Management of Sexual Dysfunction in Postmenopausal Breast Cancer Patients Taking Adjuvant Aromatase Inhibitor Therapy](/images/research/25ab87fc-a766-4e12-a06a-6982794d1da0/small/21023.jpg)
research Management of Sexual Dysfunction in Postmenopausal Breast Cancer Patients Taking Adjuvant Aromatase Inhibitor Therapy
Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
![Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One](/images/research/83cefa28-6196-4fa8-b7ac-d02826740e94/small/16903.jpg)
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
![The connection of 5-alpha reductase inhibitors to the development of depression](/images/research/a5ff3941-34fb-48fe-8272-bc15b28ec476/small/12051.jpg)
research The connection of 5-alpha reductase inhibitors to the development of depression
5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
research Hormonal and Genetic Etiology of Male Androgenetic Alopecia
research Impact of estrogens in males and androgens in females
Both estrogens and androgens are important for health in both males and females.
![Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents](/images/research/1f8ca99f-663c-451e-bfaf-4525cfd5d89c/small/17668.jpg)
research Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents
Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization
Vitamin D receptor is important for regulating hair growth and wound healing in mice.
![Polycystic Ovary Syndrome (PCOS) and Fertility](/images/research/ce8f890f-0e01-403e-8cce-fd9e63e6bedf/small/18553.jpg)
research Polycystic Ovary Syndrome (PCOS) and Fertility
PCOS affects fertility and is linked to obesity and menstrual irregularities; lifestyle changes are recommended for treatment.
![A Comprehensive Review of Acne Vulgaris](/images/research/a8b094cd-4e61-4c08-93c3-a6fae64b3444/small/13438.jpg)
research A Comprehensive Review of Acne Vulgaris
Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
research Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis
The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Endocrine Functions of the Testes
The testes produce important hormones like testosterone and others that play key roles in male body functions.
![Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression](/images/research/dbce15f4-1700-4ae7-b3e5-1fe68cd04f9e/small/31697.jpg)
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
![Novel anti‐dandruff shampoo incorporated with ketoconazole‐coated zinc oxide nanoparticles using green tea extract](/images/research/0db6acac-3e5d-4fca-b377-d714c2cc709b/small/34501.jpg)
research Novel anti‐dandruff shampoo incorporated with ketoconazole‐coated zinc oxide nanoparticles using green tea extract
The new anti-dandruff shampoo with ketoconazole-coated zinc oxide nanoparticles is more effective against dandruff.
![Hirsutism-A Comprehensive Update of Embryology, Aetiopathogenesis and Therapeutic Approach](/images/research/8b389bc4-cb44-451d-93f6-f50560caa700/small/24189.jpg)
research Hirsutism-A Comprehensive Update of Embryology, Aetiopathogenesis and Therapeutic Approach
The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
![Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter](/images/research/eff16816-51e7-414e-9f3d-68de31995edb/small/34492.jpg)
research Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter
MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.
![The Endocrine Function of the Skin: An Analytical Narrative](/images/research/e52ca5a2-471a-4b9b-aec7-e13661bd5ecb/small/29905.jpg)
research The Endocrine Function of the Skin: An Analytical Narrative
The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
research Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits
A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.
![Genetics and Epigenetics of Polycystic Ovary Syndrome](/images/research/d42e0eba-1795-4563-ab0b-cc50cae1dd70/small/26905.jpg)
research Genetics and Epigenetics of Polycystic Ovary Syndrome
Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
![Assessment of Occipital Involvement Among a Large Population of Females with Pattern Hair Loss in Saudi Arabia](/images/research/6c637ccc-6e01-4ea4-a47e-a17fc25d3f0b/small/15651.jpg)
research Assessment of Occipital Involvement Among a Large Population of Females with Pattern Hair Loss in Saudi Arabia
About one-third of Saudi women with female pattern hair loss also have thinning hair at the back of their head.
![How to Choose the Optimal Starting Dose of Clomiphene Citrate (50 or 100 mg per Day) for a First Cycle of Ovulation Induction in Anovulatory PCOS Women?](/images/research/463c7b0a-2827-477a-b687-e8b84d20635d/small/20595.jpg)
research How to Choose the Optimal Starting Dose of Clomiphene Citrate (50 or 100 mg per Day) for a First Cycle of Ovulation Induction in Anovulatory PCOS Women?
Choosing the right starting dose of Clomiphene Citrate for ovulation induction in PCOS women is challenging; higher BMI and hormone levels may indicate resistance to the standard dose.
![Drug repurposing—a promising approach for patients with angina but non-obstructive coronary artery disease (ANOCA)](/images/research/f6b38af8-900e-4e7c-b991-7bf92b6f74d4/small/20620.jpg)
research Drug repurposing—a promising approach for patients with angina but non-obstructive coronary artery disease (ANOCA)
Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
![Sex hormones modulate pathogenic processes in experimental traumatic brain injury](/images/research/442b9932-81d0-42ad-a069-8ef9c7b56a7b/small/31837.jpg)
research Sex hormones modulate pathogenic processes in experimental traumatic brain injury
Sex hormones affect brain injury differently in males and females.
![Detection of urine metabolites in polycystic ovary syndrome by UPLC triple-TOF-MS](/images/research/8fd294f4-dc4a-47c0-bc1e-096d53833ed8/small/14215.jpg)
research Detection of urine metabolites in polycystic ovary syndrome by UPLC triple-TOF-MS
Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.
![Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid](/images/research/25f9b189-ffd6-4e1f-b849-f000cbb202fb/small/36198.jpg)
research Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid
High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.