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Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Glioblastoma cells can make androgens, which might help the tumor grow.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

New genes and pathways are important for testosterone production and male sexual development.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.