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Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

AMT® is effective and safe for early-stage knee osteoarthritis.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.

Tissue-specific variation in mutant load complicates genetic counseling and prenatal diagnosis.

The conclusion introduces a new way to classify skin cysts using their shape and genetic markers.

Oral isotretinoin does not cause milia in acne patients.

Some skin conditions look like acne but are caused by drugs, and they usually get better when the drug is stopped.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

A new peptide, FOL-005, may help treat excessive hair growth by reducing a hair growth promoter, FGF7.

17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

Using lyopreserved umbilical tissue allograft may improve healing and reduce recurrence of pilonidal cysts.

Hormonal changes and conditions like polycystic ovarian syndrome are major causes of adult acne in women, with varying prevalence among different ethnicities.

People with chronic hair loss may have a higher chance of Vitamin B12 deficiency.

The document concludes that effectively managing PCOS requires a multifaceted approach.

Bald men may have higher heart disease risk.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.

Rituximab may be an effective treatment for Cronkhite-Canada syndrome with kidney disease.

Lower SHBG levels may increase the risk of PCOS.

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.