Management of Pilonidal Sinus Disease with Lyopreserved Umbilical Tissue Allograft Placement: A Case Series

This case series investigates the use of lyopreserved umbilical tissue allografts (STRAVIX PL) in managing pilonidal sinus disease in 7 patients, with 6 achieving complete wound healing within 51 to 210 days. The allografts were applied post-surgical excision, and patients were monitored for 2 to 5 months, maintaining closure for at least 18 months. The study suggests that STRAVIX PL is effective in reducing recurrence and promoting healing, offering benefits like anti-inflammatory and antimicrobial properties without needing negative pressure wound therapy. Despite promising results, the study's small sample size indicates a need for larger trials to confirm efficacy.