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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.

The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

JAK inhibitors help hair regrowth in alopecia areata but have a high risk of side effects.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Dutasteride is more effective than finasteride for hair loss treatment.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.