81 citations,
June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
660 citations,
December 2011 in “Cell” Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
19 citations,
February 2016 in “Journal of Biological Chemistry” KCNQ potassium channels help control the sensitivity of touch receptors in the skin.
142 citations,
September 2020 in “Journal of neurophysiology” Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
46 citations,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
4 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin has about 230,000 touch-sensitive nerve fibers, with high concentrations in the hands and face.
46 citations,
July 2007 in “Journal of comparative neurology” Manatee whiskers are specially adapted for touch in water.
16 citations,
December 2012 in “The Clinical Journal of Pain” Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.
1 citations,
January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
32 citations,
February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
106 citations,
February 2014 in “eLife” Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
1 citations,
June 2023 in “Cells” Exosomes could be a promising way to help repair skin and treat skin disorders.
8 citations,
October 2016 in “Journal of Investigative Dermatology” MR antagonists may improve skin health and wound healing, especially in aging.
101 citations,
January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
127 citations,
December 2005 in “Experimental Dermatology” Stress can stop hair growth in mice, and treatments can reverse this effect.
17 citations,
April 2006 in “Dermatologic Clinics” Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.
204 citations,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
15 citations,
January 2016 in “Dermatologic Clinics” Start acne treatment early to prevent scarring, consider antibiotic resistance, use maintenance therapy, and manage side effects carefully.
4 citations,
January 2018 in “Cosmetics” Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
1 citations,
March 1997 in “Journal of the American Pharmaceutical Association” Pharmacists play a key role in helping patients use over-the-counter products correctly, including those for hair regrowth and smoking cessation.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
November 2023 in “Australasian journal of dermatology” Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
60 citations,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
22 citations,
April 1985 in “Australasian Journal of Dermatology” Beta-blockers can cause rare skin side-effects, which usually improve after stopping the medication.
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
113 citations,
December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
16 citations,
March 2015 in “Clinical Cancer Research” The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
28 citations,
March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.