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Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

Diagnosing new systemic lupus during pregnancy is hard but important for the health of the mother and baby.

Antibiotics often cause skin reactions, making them a major health concern.

Mouse skin glands need healthy nerves to grow properly during hair growth phases.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Targeting the skin's endocannabinoid system could help treat skin disorders.

HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Scalp sarcoidosis can cause hair loss and needs accurate diagnosis and treatment with specific medications.

The CRH/CRH-R1 system might be involved in causing lichen planus.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

ADM scaffolds help skin heal by promoting a healing-type immune response.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.