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Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.

Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Different lab conditions and light treatment methods change how human skin cells respond to light therapy.

Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.

FUE hair transplants offer minimal scarring and are good for short hairstyles but are time-consuming and can be costly.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

New techniques for treating scalp blood vessel malformations are effective and can have good cosmetic results.

Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.

Consider benefits and risks of new alopecia treatments for safety.