158 citations,
March 2011 in “Journal of the American Academy of Dermatology” Patients with cutaneous lupus erythematosus have a severely impaired quality of life, especially emotionally.
157 citations,
August 2010 in “Lupus” The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.
149 citations,
July 2002 in “Dermatologic clinics” Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
148 citations,
February 2005 in “Autoimmunity Reviews” Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
127 citations,
September 1996 in “British Journal of Dermatology” Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.
74 citations,
March 2001 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.
52 citations,
March 2007 in “Dermatologic Therapy” The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.
33 citations,
March 2018 in “Italian Journal of Dermatology and Venereology” Cutaneous lupus erythematosus is a chronic skin disease that can progress to systemic lupus in some cases and requires treatment to prevent recurrences and scarring.
31 citations,
January 2009 in “Autoimmunity Reviews” Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
27 citations,
February 2009 in “Autoimmunity Reviews” The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.
25 citations,
June 2009 in “British Journal of Dermatology” Early scar classification in lupus can improve treatment and patient outcomes.
23 citations,
November 2013 in “Lupus” Therapeutic intervention improved the quality of life for Japanese lupus patients with skin issues.
19 citations,
September 2010 in “Journal of the European Academy of Dermatology and Venereology” The CLASI is useful but needs revision to accurately assess all cutaneous lupus erythematosus subtypes.
18 citations,
July 2016 in “British Journal of Dermatology” Cutaneous lupus erythematosus greatly reduces patients' quality of life.
16 citations,
June 2017 in “JAMA Dermatology” Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.
14 citations,
November 2016 in “Lupus” Lenalidomide effectively and safely treats skin symptoms in pediatric lupus, reducing the need for prednisone.
12 citations,
January 2017 in “Skin appendage disorders” Two patients with skin lupus were mistakenly thought to have a different scalp condition but improved with lupus treatment.
9 citations,
February 2011 in “Biologics: Targets & Therapy” Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.
8 citations,
February 2022 in “Frontiers in Medicine” COVID-19 may trigger severe skin flare-ups in people with autoimmune conditions like lupus.
3 citations,
December 2019 in “Lupus” Hydroxychloroquine effectively treated a woman's lupus skin issues and hair loss.
2 citations,
January 2006 in “Technical report” The document concludes that better tools are needed to measure skin disease severity in dermatomyositis and cutaneous lupus erythematosus, and introduces the DSSI and CLASI as reliable instruments.
1 citations,
January 2022 in “Advances in Dermatology and Allergology” Most patients with cutaneous lupus erythematosus in Bangladesh are young women, with chronic forms and photosensitivity being common.
1 citations,
January 2021 in “Journal of the American Academy of Dermatology” Careful histologic examination is crucial to differentiate types of bullous lesions in cutaneous lupus erythematosus.
September 2023 in “Clinical, cosmetic and investigational dermatology” A patient with a rare form of lupus improved after treatment for skin ulcers and hair loss on the face and scalp.
Many patients with cutaneous lupus erythematosus experience hair loss and nail problems, which are important for diagnosis and treatment.
April 2023 in “Journal of Investigative Dermatology” PTEN was identified as a specific marker for the skin disease cutaneous lupus erythematosus, and it helps increase the expression of harmful type I interferons.
January 2022 in “Skin Appendage Disorders” Areata-like lupus can mimic alopecia areata but is a form of cutaneous lupus erythematosus.
November 2021 in “Chattagram Maa-O-Shishu Hospital Medical College Journal” Most patients with Cutaneous Lupus Erythematosus are young females, and dermatologists play a key role in diagnosis.
January 2018 in “Przegla̧d dermatologiczny” The Polish Dermatological Society recommends personalized treatment for cutaneous lupus, including lifestyle changes, medications, and monitoring, with specific drugs for severe cases.