TLDR Cutaneous lupus erythematosus greatly reduces patients' quality of life.
Cutaneous lupus erythematosus (CLE) significantly impaired health-related quality of life (HRQoL) in patients, with symptoms including pain, pruritus, fatigue, and photosensitivity. A systematic review identified 482 citations, with 11 studies meeting inclusion criteria, using five patient-reported outcome (PRO) instruments: Skindex (versions 16 and 29), Dermatology Life Quality Index, 36-Item Short-Form Health Survey, and visual analogue scales for pain and pruritus. The review highlighted the limited number of studies on PRO in CLE and emphasized the need for further research to better understand the disease's impact from patients' perspectives.
28 citations,
January 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Women with scarring alopecia have a lower quality of life and more anxiety and depression than those with non-scarring alopecia.
23 citations,
November 2013 in “Lupus” Therapeutic intervention improved the quality of life for Japanese lupus patients with skin issues.
158 citations,
March 2011 in “Journal of the American Academy of Dermatology” Patients with cutaneous lupus erythematosus have a severely impaired quality of life, especially emotionally.
61 citations,
March 2009 in “The Journal of the American Board of Family Medicine” Early diagnosis and treatment of discoid lupus erythematosus improve outcomes.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
148 citations,
February 2005 in “Autoimmunity Reviews” Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.
