Evaluation of the Quality of Life of Lupus Erythematosus Patients with Cutaneous Lesions in Japan

November 2013 in “ Lupus ”

Mariko ISHIGURO, Hideo Hashizume, Takaharu Ikeda, Yuki Yamamoto, Fukumi Furukawa

lupus erythematosus cutaneous lesions Skindex-29 CLASI indices acute phase skin activity systemic lupus erythematosus LE SLE

TLDR Therapeutic intervention improved the quality of life for Japanese lupus patients with skin issues.

The study evaluated the quality of life (QOL) of 54 Japanese lupus erythematosus (LE) patients with cutaneous lesions using the Skindex-29 and CLASI tools. Results showed that therapeutic interventions improved QOL. Female gender was a significant risk factor for poor QOL in "Functioning" before treatment, and poor QOL was also associated with female gender in "Emotions" and older age in "Symptoms" before treatment, and longer SLE duration in "Functioning" after treatment. Acute phase skin activity correlated with poor emotional and functional QOL. This was the first report on the QOL of Japanese LE patients, despite the small cohort.

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Research cited in this study

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