Clinicopathological Characteristics of Cutaneous Lupus Erythematosus Patients in Bangladesh

January 2022 in “ Advances in Dermatology and Allergology ”

Mohammad Rafiqul Mowla, Deva Pratim Barua, Shakila Zaman, Mohammad Ismail Hossain Chowdhury, Shamim Ara, Adam Reich

cutaneous lupus erythematosus chronic cutaneous lupus erythematosus acute cutaneous lupus erythematosus subacute cutaneous lupus erythematosus photosensitivity discoid rash non-scarring alopecia antinuclear antibodies CLE CCLE ANA

TLDR Most patients with cutaneous lupus erythematosus in Bangladesh are young women, with chronic forms and photosensitivity being common.

This study describes the clinical and pathological characteristics of 218 patients with cutaneous lupus erythematosus (CLE) in Bangladesh, with a female predominance (85.8%) and a mean age of 30 years. Chronic cutaneous lupus erythematosus (CCLE) was the most common subtype (70.6%), followed by acute (21.1%) and subacute (8.3%) forms. Photosensitivity (90.8%) and discoid rash (71.1%) were the most frequent skin manifestations, while non-scarring alopecia (56.4%) was the most common non-specific lesion. Antinuclear antibodies (ANA) were the most prevalent autoantibodies (60.5%). The study highlights distinct clinical and pathological features among different CLE subtypes.

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research The Spectrum of Cutaneous Manifestations in Lupus Erythematosus: The Italian Experience

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