Clinicopathological Characteristics of Cutaneous Lupus Erythematosus Patients in Bangladesh

January 2022 in “ Advances in Dermatology and Allergology ”

Mohammad Rafiqul Mowla, Deva Pratim Barua, Shakila Zaman, Mohammad Ismail Hossain Chowdhury, Shamim Ara, Adam Reich

cutaneous lupus erythematosus chronic cutaneous lupus erythematosus acute cutaneous lupus erythematosus subacute cutaneous lupus erythematosus photosensitivity discoid rash non-scarring alopecia antinuclear antibodies CLE CCLE ANA

TLDR Most patients with cutaneous lupus erythematosus in Bangladesh are young women, with chronic forms and photosensitivity being common.

This study describes the clinical and pathological characteristics of 218 patients with cutaneous lupus erythematosus (CLE) in Bangladesh, with a female predominance (85.8%) and a mean age of 30 years. Chronic cutaneous lupus erythematosus (CCLE) was the most common subtype (70.6%), followed by acute (21.1%) and subacute (8.3%) forms. Photosensitivity (90.8%) and discoid rash (71.1%) were the most frequent skin manifestations, while non-scarring alopecia (56.4%) was the most common non-specific lesion. Antinuclear antibodies (ANA) were the most prevalent autoantibodies (60.5%). The study highlights distinct clinical and pathological features among different CLE subtypes.

View this study on termedia.pl →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research The Spectrum of Cutaneous Manifestations in Lupus Erythematosus: The Italian Experience

132 citations, July 2000 in “Lupus”

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

Related Community Posts Join

6 / 12 results

community How do you use rosemary oil and peppermint oil?

in Question 6 upvotes 4 years ago

Rosemary oil and peppermint oil may promote hair growth and increase cutaneous blood flow, showing promise as treatments for androgenetic alopecia. Minoxidil 2% is also used for treating hair loss.

community Scientific evidence for Peppermint & Rosemary oils + My Experience

in Research/Science 114 upvotes 2 years ago

Natural treatments for hair loss, specifically peppermint oil and rosemary oil; how they can be used as a supplementary or alternative treatment to pharmaceuticals such as finasteride and minoxidil; and the personal experience of the user Divallo, who has seen an increase in density and thickness after using these oils for around 2.5 years. The post also touches on the potential antifungal properties of the oils and their effects on cutaneous blood flow.

community high bloodpressure and crown thinning in early 20s

in Is this regrowth? 9 upvotes 6 months ago

A user with kidney disease and high blood pressure experienced hair thinning, especially around the vertex. They are currently using finasteride and oral minoxidil but are considering whether to resume blood pressure medication despite managing symptoms with diet and exercise.

community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

in Research/Science 112 upvotes 1 year ago

Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Why is everyone not directly advised Dutasteride?

in Finasteride/Dutasteride 167 upvotes 2 months ago

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

Related Research

1 / 1 results

research Bullous Lesions in Patients with Cutaneous Lupus Erythematosus: A Clinicopathologic Study

1 citations, January 2021 in “Journal of the American Academy of Dermatology”

Careful histologic examination is crucial to differentiate types of bullous lesions in cutaneous lupus erythematosus.