36 citations,
April 2018 in “Journal of Investigative Dermatology” Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
35 citations,
June 2018 in “Urology” The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
35 citations,
October 2015 in “International Journal of Pharmaceutics” Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
34 citations,
April 1973 in “The American journal of clinical nutrition” Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.
32 citations,
December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
32 citations,
June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
30 citations,
December 2018 in “International Journal of Biological Macromolecules” Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.
30 citations,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
30 citations,
October 2015 in “Journal of Ethnopharmacology” Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
29 citations,
December 2017 in “Molecular therapy” Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
27 citations,
March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
26 citations,
December 2021 in “Regenerative Biomaterials” The hydrogel speeds up skin wound healing and helps regenerate tissue.
26 citations,
September 2018 in “Neurobiology of Disease” Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
26 citations,
September 2018 in “Colloids and Surfaces B: Biointerfaces” A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.
26 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
24 citations,
April 2017 in “Journal of Investigative Dermatology” Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.
23 citations,
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” NF-κB is crucial for different stages and types of hair growth in mice.
23 citations,
October 1988 in “Clinics in Dermatology” Minoxidil was first made for high blood pressure, but it was later found to help hair growth.
21 citations,
October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
21 citations,
December 2016 in “European journal of pharmaceutics and biopharmaceutics” Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.
20 citations,
September 2018 in “Journal of colloid and interface science” Modified keratin binds better to hair, especially bleached hair.
20 citations,
September 2015 in “Protein expression and purification” Scientists made safflower seeds produce a human growth factor that could help with hair growth and wound healing.
19 citations,
March 2018 in “Journal of Investigative Dermatology” The gene Msx2 is crucial for hair follicle regeneration during wound healing.
19 citations,
October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.
18 citations,
September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
18 citations,
December 2016 in “Phytomedicine” Curcuma aeruginosa essential oil effectively reduces hair growth and lightens underarm skin.
18 citations,
November 2016 in “Neuromuscular Disorders” Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.
18 citations,
November 2016 in “Journal of Oral and Maxillofacial Surgery” Platelet-Rich Plasma (PRP) treatment can potentially increase hair density and quality in people with hair loss, but more research is needed to confirm its effectiveness.
17 citations,
June 2019 in “Cellular signalling” Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.