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![Skin Steroidogenesis in Health and Disease](/images/research/38c91137-04e7-4c70-8ca1-baac66c18b75/small/14111.jpg)
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
![The Role of Medical Language in Changing Public Perceptions of Illness](/images/research/78f0eb98-9bb0-4477-ad5d-cdb2958631c8/small/15017.jpg)
research The Role of Medical Language in Changing Public Perceptions of Illness
Medical terms make new health issues seem more serious but don't affect views on well-known conditions.
![Antiandrogen Therapy in Dermatology](/images/research/a251001b-53e0-48a7-9632-f8d05b2a148c/small/21042.jpg)
research Antiandrogen Therapy in Dermatology
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
![No Metabolic Impact of Surgical Normalization of Hyperandrogenism in Postmenopausal Women with Ovarian Androgen-Secreting Tumors](/images/research/e79c6d64-3699-483a-a5dd-dcd5718cb8ea/small/14523.jpg)
research No Metabolic Impact of Surgical Normalization of Hyperandrogenism in Postmenopausal Women with Ovarian Androgen-Secreting Tumors
Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.
![Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Lifestyle Habits](/images/research/3ff368d4-4f9b-470c-b883-a3727833ec27/small/4733.jpg)
research Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Lifestyle Habits
Men with hair loss have higher BMI, waist size, blood pressure, and are linked to smoking and inactivity.
![Serum C-19 Steroid Sulphates in Females with Clinical Hyperandrogenism](/images/research/47b7dd8b-2df6-481c-a98d-862ea78d0aca/small/21160.jpg)
research Serum C-19 Steroid Sulphates in Females with Clinical Hyperandrogenism
Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
![Coronary Risk in Androgenetic Alopecia](/images/research/3c6b67d1-b8a2-460c-b337-416ba3610607/small/18916.jpg)
research Coronary Risk in Androgenetic Alopecia
Male pattern baldness is not a risk factor for heart disease based on cholesterol levels alone.
![Effectiveness of Terbinafine in Treating Toenail Onychomycosis and Associated Studies](/images/research/9902c9a1-7254-4d94-95d3-9c045bc14b4b/small/20432.jpg)
research Effectiveness of Terbinafine in Treating Toenail Onychomycosis and Associated Studies
Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.
![Screening for 21-Hydroxylase-Deficient Nonclassic Adrenal Hyperplasia Among Hyperandrogenic Women: A Prospective Study](/images/research/8b777ce0-73a0-4b97-92b0-f1bd0ca23fe3/small/15538.jpg)
research Screening for 21-Hydroxylase-Deficient Nonclassic Adrenal Hyperplasia Among Hyperandrogenic Women: A Prospective Study
Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.
![A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism](/images/research/6f5fdeed-099c-476e-8529-8a5ddbd1dff3/small/2227.jpg)
research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
![Physiological Changes in the Skin During Pregnancy](/images/research/97b3c562-9b65-40a1-80ef-3892941012f3/small/25264.jpg)
research Physiological Changes in the Skin During Pregnancy
Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.
![A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity](/images/research/4fca6c7a-15bb-4b29-ac99-93890fc4043b/small/20447.jpg)
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
![Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism](/images/research/c64d57e6-9c11-4125-8830-185c9e3044cb/small/2191.jpg)
research Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism
Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
![Primary Generalized Glucocorticoid Resistance And Hypersensitivity](/images/research/be9fffb5-c1a1-4b68-911c-355bf76c6503/small/20347.jpg)
research Primary Generalized Glucocorticoid Resistance And Hypersensitivity
The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
![Minoxidil: Right Atrial Cardiac Pathology in Animals and Humans](/images/research/54866b2d-59fb-4df8-b852-f6c1ff05a09d/small/1796.jpg)
research Minoxidil: Right Atrial Cardiac Pathology in Animals and Humans
Minoxidil may cause heart issues in animals and humans.
![Finasteride Cream in Hirsutism](/images/research/aba220ed-9703-4520-823a-85d1f2453afd/small/2326.jpg)
research Finasteride Cream in Hirsutism
Finasteride cream reduces hair growth in women with hirsutism, but more research needed.
![Alterations in Androgen Conjugate Levels in Women and Men with Alopecia](/images/research/56f8d3a6-257a-4574-8eff-bf370fcb741a/small/21073.jpg)
research Alterations in Androgen Conjugate Levels in Women and Men with Alopecia
People with hair loss may have different levels of certain hormones due to changes in hormone processing.
![Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica](/images/research/e68ea210-b0d5-43c8-a3cc-8c9b585c503f/small/1860.jpg)
research Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica
Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.
![A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism](/images/research/43fc83be-8aff-419f-bdb5-36c09a32799d/small/2222.jpg)
research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.
![Safety of 5α-Reductase Inhibitors and Spironolactone in Breast Cancer Patients Receiving Endocrine Therapies](/images/research/67dcb43c-67cb-4d87-8936-967958e613cd/small/17815.jpg)
research Safety of 5α-Reductase Inhibitors and Spironolactone in Breast Cancer Patients Receiving Endocrine Therapies
The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.
![Hair Loss and Hirsutism in the Elderly](/images/research/3083eada-c324-42aa-a021-0bd13a0f45b8/small/15447.jpg)
research Hair Loss and Hirsutism in the Elderly
Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.
![Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women](/images/research/4378125e-fb46-4d2f-810d-2f3d20a15ce5/small/2042.jpg)
research Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
![Minoxidil in Breast Milk](/images/research/6f96e6a2-1ef9-4224-ac43-cf034e7aab60/small/1831.jpg)
research Minoxidil in Breast Milk
Minoxidil in breast milk may harm nursing infants.
![Systemic Causes of Hair Loss](/images/research/6c616402-8e1e-4253-adad-bba704401a2a/small/14053.jpg)
research Systemic Causes of Hair Loss
The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.
![AKR1D1 Regulates Glucocorticoid Availability and Glucocorticoid Receptor Activation in Human Hepatoma Cells](/images/research/4c559e21-fc92-498a-a978-4bc05f194cc3/small/31828.jpg)
research AKR1D1 Regulates Glucocorticoid Availability and Glucocorticoid Receptor Activation in Human Hepatoma Cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
![Effectiveness of Ethinylestradiol/Chlormadinone Acetate in Treating Dermatological Conditions Related to High Androgen Levels](/images/research/b798499a-9bf9-4305-a83b-4ba8ce9a9868/small/16306.jpg)
research Effectiveness of Ethinylestradiol/Chlormadinone Acetate in Treating Dermatological Conditions Related to High Androgen Levels
The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.
![Influence of Genotype and Hyperandrogenism on Sexual Function in Women With Congenital Adrenal Hyperplasia](/images/research/50b23a74-fe8b-48ed-bbf3-e8bd46b4f6ce/small/13509.jpg)
research Influence of Genotype and Hyperandrogenism on Sexual Function in Women With Congenital Adrenal Hyperplasia
Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.
![Focal and Generalized Alopecia in Cats: Causes, Diagnosis, and Treatment](/images/research/e5925e94-2228-41d1-92cb-84bc6a5e71a1/small/25297.jpg)
research Focal and Generalized Alopecia in Cats: Causes, Diagnosis, and Treatment
The document concludes that hair loss in cats is caused by various factors, including allergies, mites, infections, and hormonal issues, with treatments varying accordingly.
![Defining the Transcriptional Signature of Esophageal-to-Skin Lineage Conversion](/images/research/9aeb1265-909e-49c6-8a0e-2befac569e31/small/30716.jpg)
research Defining the Transcriptional Signature of Esophageal-to-Skin Lineage Conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.