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Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.

Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.

Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.

SSRIs can cause hair loss, especially sertraline, with higher risk in women.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Protein hydrolysates applied to roots or leaves differently improved lettuce yield and quality, with the best results seen in specific combined treatments for each type.

Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.

Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.

NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.

The document concludes that accurate diagnosis of hair loss in children is crucial due to limited treatment options and the condition's psychological impact.

Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.

Hair restoration surgery can have complications; success depends on patient education, careful planning, and proper execution.

Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.

Melanoma survivors are more likely to use sunscreen and seek shade than others, but less than half often use sunscreen and avoid the sun, and some still use tanning beds.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Transcutol P best increases Finasteride absorption for hair loss treatment.

Repigmentation in vitiligo may come from melanocyte stem cells in the skin.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.